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0167-5273/$ - see front matter © 2007 Elsevier Ireland Ltd. All rights reserved.
doi:10.1016/j.ijcard.2007.08.094
Prevalence and treatment of proximal left subclavian artery stenosis in
patients referred for coronary artery bypass surgery
Amit Prasad
a
, Anand Prasad
b
, Indu Varghese
b
, Michele Roesle
b
,
Subhash Banerjee
b
, Emmanouil S. Brilakis
b,
⁎
a
Department of Internal Medicine, University of Texas Southwestern Medical School, United States
b
Division of Cardiovascular Diseases, University of Texas Southwestern Medical School and Department of Cardiology Dallas VA Medical Center, Dallas,
Texas, United States
Received 27 July 2007; accepted 10 August 2007
Available online 26 December 2007
Abstract
The left internal mammary artery (LIMA) is currently used in most coronary artery bypass graft (CABG) surgeries due to excellent long-
term patency. Left subclavian artery stenosis (SAS) proximal to the LIMA origin can cause a steal syndrome leading to myocardial ischemia
or LIMA failure. We retrospectively evaluated the records of 608 consecutive patients referred for CABG at our institution between October
1, 2004 and October 1, 2006 and identified 226 patients (37%) who underwent left subclavian angiography immediately after diagnostic
coronary angiography. Significant left SAS was found in 6 of those 226 patients (2.7%). Subclavian angiography did not result in any
complications. All left SAS lesions were successfully stented, followed by CABG surgery (using the LIMA artery) after 22 ± 7 days. Left
subclavian angiography in patients referred for coronary artery bypass surgery has low risk and may identify a small proportion of patients
with significant proximal left SAS. Stenting of proximal left SAS can be accomplished before CABG with low risk and excellent short-
term outcomes.
© 2007 Elsevier Ireland Ltd. All rights reserved.
Keywords: Subclavian artery stenosis; Coronary subclavian steal syndrome; Coronary artery bypass surgery
⁎
Corresponding author. Dallas VA Medical Center (111A), 4500 South
Lancaster Road, Dallas, TX 75216, United States. Tel.: +1 214 857 1547;
fax: +1 214 302 1341.
E-mail address: emmanouil.brilakis@utsouthwestern.edu (E.S. Brilakis).
The left internal mammary artery (LIMA) is currently
used in almost all coronary artery bypass graft (CABG)
surgeries. Left subclavian artery stenosis (SAS) proximal to
the LIMA origin could obstruct the LIMA blood flow and
lead to myocardial ischemia and LIMA failure [1,2].
Although subclavian angiography can aid in diagnosis and
treatment of proximal SAS [1] it has not gained widespread
acceptance in part because it carries some risk [3,4].
Percutaneous SAS treatment may have high restenosis
rates [5,6], and surgical intervention has been proposed as
a more durable option [7,8].
We retrospectively reviewed the medical records and
coronary angiograms of 608 consecutive patients referred for
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