IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 15, Issue 7 Ver. XI (July. 2016), PP 42-44 www.iosrjournals.org DOI: 10.9790/0853-1507114244 www.iosrjournals.org 42 | Page Comparison of duration of maternal hospital stay in conservative & aggressive management of Preterm prelabor rupture of membranes(PPROM) in Indian women at 34-36 weeks gestation. Shachi Shukla 1 , Kshitij Sharma 2 1 Resident, Department of Obstetrics &Gynaecology, SMS Medical College, Jaipur(Rajasthan), India. 2 Department of civil engineering, Indian Institute of Technology, Kanpur, (Uttar Pradesh), India Abstract: Aim:To compare the conservative and aggressive management of Preterm prelabor rupture of membranes (PPROM) in Indian women at 34-36 weeks gestation in terms of duration of their hospital stay. Materials & Method:194 pregnant women with PPROM at gestational age 34-36 weeks admitted in labour ward were included in the study conducted from 2009 -2010 in department of Obstetrics & Gynaecology, SMS Medical College, India. Random allocation to conservative & aggressive management group was done by offering Chit Box Method assigning 97 cases in each group. In conservative management cases were hospitalized& provided bed rest, Daily fetal monitoring, maternal vitals monitoring, Oral tab erythromycin 500 mg t.d.s for 7 days, Daily WBC count and C - reactive protein estimation. Expectant management was abandoned if there was clinical evidence of labour, infection or fetal distress. In aggressive management induction of labour was done by Tab Misoprostol 25 g orally, at 4-6 hour intervals, for a maximum of 5 doses. Caesarean delivery was performed for standard obstetrical indication and for failed induction. After delivery neonatal care was provided by neonatologist Results:Out of total 97 cases, in aggressive management, majority 73 (75.26%) cases had duration  5 days, 19 (19.59%) up to 6-10 days and 5 (5.15%) cases up to 11+ days. Similarly out of total 97 cases in conservative management, majority 46 (47.42%) cases had duration  5 days, 33 (34.02%) up to 6-10 days and 18 (18.56%) cases up to 11+ days. The mean duration of hospital stay of mother in aggressive management were 4.10  3.10 days and in conservative management it is 7.21  3.36 days. Conclusion:Majority of cases in both aggressive and conservative management group had duration of hospital stay of  5 days. But the total duration of hospital stay of mother were much higher in conservative management group in present study. Thus mean duration of hospital stay of mother were much higher in conservative management group as compared to aggressive management. Keywords-PPROM, conservative, aggressive, hospital stay. I. Introduction Preterm prelabor rupture of fetal membranes (PPROM) is defined as rupture of fetal membranes prior to the onset of labour at less than 37 weeks of gestation. The fetal membranes serve as a barrier to ascending infection. Once the membranes rupture, both the mother and foetus are at risk of infection and of other complications. Most women with PPROM go into spontaneous labour within 24 hours of rupturing their membranes, but 6% of women will not be in spontaneous labour within 96 hours. However earlier in gestation the rupture occurs, the less likely that the onset of labour will be within a specified time period. PPROM occurs in 2 to 3% of all pregnancies and proceeds 1/3 of preterm births and 18 to 20% of perinatal deaths. PPROM is largely a clinical diagnosis characterised by a history of watery vaginal discharge. Prolonged rupture of membrane (PROM) is an important risk factor for chorioamnionitis.Chorioamnionitis is a common complication of pregnancy associated with significant maternal, perinatal, and long-term adverse outcomes. Adverse maternal outcomes include postpartum infections and sepsis while adverse infant outcomes include stillbirth, premature birth, neonatal sepsis, chronic lung disease and brain injury leading to cerebral palsy and other neurodevelopmental disabilities Conservative versus aggressive management of PPROM is amongst the most controversial issue and still remains a major dilemma to the obstetricians. Present study is intended to compare the conservative and aggressive management of PPROM at 34-36 weeks gestation in terms of duration of hospital stay.