Steroid resistant inflammation in a rat model of COPD is associated with a lack of NF-κB activation. Mark A. Birrell, Sissie Wong, David J. Hele, Kerryn McCluskie, Elizabeth Hardaker and Maria G. Belvisi Respiratory Pharmacology Group, National Heart & Lung Institute, Faculty of Medicine, Imperial College, Dovehouse Street, London SW3 6LY, UK. Author for correspondence and requests for reprints: Professor Maria G. Belvisi, Respiratory Pharmacology Group, National Heart & Lung Institute, Faculty of Medicine, Imperial College, Dovehouse Street, London SW3 6LY, UK. Tel. 0207-351-8270 Fax 0207-351-8173 Email m.belvisi@imperial.ac.uk This work was supported by The Harefield Trust, UK Running title: Steroid, neutrophilia and emphysema. Descriptor number: 172 Word count for the body of the manuscript: 4842 We are very grateful to Buxco Europe Ltd for the loan of a forced manoeuvres machine AJRCCM Articles in Press. Published on March 31, 2005 as doi:10.1164/rccm.200409-1257OC Copyright (C) 2005 by the American Thoracic Society.