doi:10.1016/j.jemermed.2007.11.111
Clinical
Communications: Adults
UNUSUAL ETIOLOGY OF EPIGASTRIC PAIN
Rita Slim, MD,* Tarek Smayra, MD,† Cyril Tohme, MD,‡ Elia Samaha, MD,* Cesar Yaghi, MD,*
and Raymond Sayegh, MD*
*Department of Gastroenterology, †Department of Radiology, and ‡Department of General Surgery, Hotel-Dieu de France Hospital,
Beirut, Lebanon
Reprint Address: Rita Slim, MD, Department of Gastroenterology, Hotel-Dieu de France Hospital, Beirut, Lebanon
e Abstract—Background: Epigastric pain is a common
presenting complaint encountered in urgent care settings.
Although peptic, biliary, and pancreatic pathologies are the
most frequent findings, other rare diagnoses also can be
found. Objectives: We report an unusual case of acute
epigastric pain in which abdominal ultrasound was of great
support in revealing the diagnosis. Case Report: A 64-year-
old man presented to the Emergency Department after
rapid onset of acute epigastric pain. Abdominal ultrasound
showed a multi-cystic heterogeneous mass between the
stomach and the liver. Abdominal computed tomography
scan confirmed the gastric origin of the mass and showed
torsion signs. Urgent laparotomy was performed with tu-
mor excision. The diagnosis of pedunculated exophytic gastric
stromal tumor was made and long-term follow-up was ar-
ranged. Conclusions: Acute presentation revealed the pres-
ence of the tumor, which was excised surgically. © 2011
Elsevier Inc.
e Keywords— epigastric pain; torsion; GIST
INTRODUCTION
Gastrointestinal stromal tumors (GIST) were described
in 1983 as a mesenchymal neoplasm closely related to
the interstitial cells of Cajal (1). Diagnosis of GIST relies
on standard histological examination. In a typical case,
the diagnosis is definitively established when CD34 and
c-Kit are positive while alpha-smooth muscle actin and
S-100 are negative (2).
Cystic stromal degeneration and stromal hemorrhage
represent prominent features of GIST with spindle cell
type. We describe a case of acute epigastric pain due to
the pedicle torsion of an exophytic gastric stromal tumor,
asymptomatic before this acute presentation.
CASE REPORT
A 64-year-old man with an unremarkable past medical
history presented with acute abdominal pain. Sixteen
hours before admission, he reported an acute epigastric
pain of rapidly increasing intensity unrelated to meals,
with no referred pain. There were neither changes in
bowel habits nor signs of gastrointestinal hemorrhage.
His clinical examination revealed stable hemodynamics
with a temperature of 36.9°C (98.4°F) axillary, pulse 70
beats/min, blood pressure 130/80 mm Hg, and respira-
tory rate 18 breaths/min. The heart and lungs were nor-
mal on auscultation, and abdominal examination showed
localized epigastric tenderness with a negative Murphy
sign. Routine laboratory data were normal, including
blood count and cardiac and liver enzymes. Electrocar-
diogram and chest radiograph were also normal.
Abdominal sonography showed a 6-cm heterogeneous
multi-cystic abdominal mass located between the stom-
ach and the left lobe of the liver (Figure 1). Abdominal
computed tomography (CT) scan revealed a solid mass
attached to the anterior wall of the stomach with torsion
signs (Figure 2).
RECEIVED: 30 September 2007; FINAL SUBMISSION RECEIVED: 5 November 2007;
ACCEPTED: 16 November 2007
The Journal of Emergency Medicine, Vol. 40, No. 5, pp. e93– e95, 2011
Copyright © 2011 Elsevier Inc.
Printed in the USA. All rights reserved
0736-4679/$–see front matter
e93