Hossain et al., IJPSR, 2011; Vol. 2(4): 1040-1045 ISSN: 0975-8232 Available online on www.ijpsr.com 1040 IJPSR (2011), Vol. 2, Issue 4 (Research Article) Received on 04 January, 2011; received in revised form 12 March, 2011; accepted 22 March, 2011 STUDIES ON ANTIBACTERIAL, CYTOTOXIC AND ANTIOXIDANT PROPERTIES OF THE SEEDS AND LEAVES OF FICUS RACEMOSA Salman Bin Hosain* 1 , Shapna Sultana 2 and Afroza Haque 2 Atish Dipankar University of Science and Technology 1 , Manik Nagar, Dhaka, Bangladesh Department of Pharmacy, Southeast University 2 , Banani, Dhaka, Bangladesh ABSTRACT The seeds and leaves of Ficus racemosa have shown considerable antioxidant and cytotoxicity properties while their antibacterial activities were found low. The extracts were found to have different levels of antioxidant and cytotoxicity properties in different concentration. For antioxidant activity, here we used free radial scavenging activity of plant extracts against stable DPPH (1, 1-diphenyl 2-picrylhydrazyl) which was determined spectrophotometrically by the method described in Brand William et al. (1995). Methanolic extracts of these plants were used. As we know that ascorbic acid is a perfect antioxidant, that’s ǁhy it ǁas used as a standard reference. The absorbance was taken at 517nm by UV spectrophotometer. The IC 50 (Inhibitory Concentration) value of standard was 8.287µg/ml. The IC 50 value of Ficus racemosa seeds and leaves were 3.893µg/ml and 14.5µg/ml respectively. For Cytotoxicity, brine shrimp lethality bioassay was used. We used Vincristine sulfate as a standard reference. The LC 50 value of standard was 0.057µg/ml. The LC 50 (Lethal Concentration) value of the seeds and leaves were 0.56µg/ml and 0.467µg/ml respectively. The plant has shown significant activities against Surcina lutea. Correspondence to Author: Salman Bin Hosain Atish Dipankar University of Science and Technology, Manik Nagar, Dhaka, Bangladesh Keywords: Antibacterial, Cytotoxicity, Antioxidant, Ficus Racemosa