Predictors of the Need for Critical Care After Total Joint Arthroplasty:
An Update of Our Institutional Risk Stratification Model
P. Maxwell Courtney, MD
a
, Colin M. Whitaker, BS
a
, Jacob T. Gutsche, MD
b
,
Eric L. Hume, MD
a
, Gwo-Chin Lee, MD
a
a
Department of Orthopaedic Surgery, University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
b
Department of Anesthesiology and Critical Care, University of Pennsylvania, Penn Presbyterian Medical Center, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
abstract article info
Article history:
Received 3 February 2014
Accepted 21 February 2014
Available online xxxx
Keywords:
total joint arthroplasty
complications
intensive care unit
risk stratification
Based on our previously published risk stratification model, 295 (19%) of a consecutive series of 1594 TJA
patients were triaged to the ICU. However, only 67 patients (22%) required intensive care interventions. We
identified 5 independent multivariate predictors (P b 0.001) including COPD, CAD, CHF (1 point each),
EBL N 1000 mL, and intraoperative vasopressors (2 points each) to form the Penn Arthroplasty Risk Score
(PARS). Patients with a score of 0 through 7 had a probability of requiring critical care of 7.0%, 13.2%, 23.5%,
38.1%, 55.4%, 71.4%, 83.4%, and 91.1% respectively. Based on these results, our previous risk stratification
protocol is overly sensitive and non-specific. Any risk stratification algorithm for ICU admission should
include intraoperative risk factors in order to be fully predictive.
© 2014 Elsevier Inc. All rights reserved.
With the number of total joint arthroplasties projected to reach
4 million annually by 2030 [1], hospitals can be expected to allocate
an increasing amount of critical care services to orthopaedic
patients. Estimated hospital costs associated with total joint
arthroplasty (TJA) reached $30 billion in 2004 and are expected to
continue to increase. [1] Although TJA is widely regarded as a
successful surgery with excellent patient outcomes, complications
including pulmonary embolism, acute renal failure, tachyarrhythmia,
and myocardial infarction can occur [2,3]. While one study supports
improved outcomes when these patients are co-managed with
internal medicine physicians [4], it is unclear which patients require
a higher level of critical care monitoring. Determination of who
should be triaged to the intensive care unit (ICU) postoperatively
represents an important decision point with regard to patient safety
and hospital resources.
As advances in modern medicine have increased life expectancy,
older patients with more medical comorbidities are undergoing total
joint arthroplasties [5]. Studies have shown an increased complication
rate after TJA in patients with diabetes, hypertension, obesity, and
higher American Society of Anesthesiologists score [6–9]. Two studies
have reported a rate of major adverse events such as pulmonary
embolism, tachyarrhythmia, and myocardial infarction between 1.7%
and 4.6% after TJA [2,10].
Although one study found that 58% of patient who experienced a
serious medical complication after TJA had no predisposing risk
factors [11], identifying at risk patients preoperatively can improve
patient outcomes and decrease mortality. At our institution, Kamath
and colleagues developed a model based on preoperative risk factors
to stratify patients undergoing elective THA and demonstrated that
this protocol significantly reduced mortality and unplanned admis-
sions to the ICU [13,14].
However, while this initiative has improved patient safety at our
institution, a significant number of patients were triaged to the ICU
unnecessarily; increasing cost and straining hospital resources. This
study aims to determine the “at risk” patient following arthroplasty
in order to triage them appropriately to areas where a higher level of
monitoring or interventions could be delivered. Therefore, the
purpose of our study is to 1) evaluate the number of patients
triaged to ICU actually requiring critical care interventions; 2)
identify intraoperative risk factors that contribute to increased
critical care requirements; and 3) develop a new model taking into
account intraoperative factors to refine our risk stratification
algorithm to maximize patient safety and minimize waste of critical
care resources.
Patients and Methods
No outside funding was received for this study and the study was
approved and conducted according to the guidelines set forth by our
Institutional Review Board (IRB). We identified 1594 consecutive
patients who underwent an elective total hip or knee arthroplasty
procedure at a single, high-volume, academic institution from January
2012 through February 2013. Using a prospectively collected patient
database, we identified all patients who were admitted to the ICU
during the study period. Patients were risk stratified to postoperative
The Journal of Arthroplasty xxx (2014) xxx–xxx
The Conflict of Interest statement associated with this article can be found at http://
dx.doi.org/10.1016/j.arth.2014.02.028.
Reprint requests: Gwo-Chin Lee, MD, Department of Orthopaedic Surgery, Penn
Presbyterian Medical Center, Philadelphia, PA 19104.
0883-5403/0000-0000$36.00/0 – see front matter © 2014 Elsevier Inc. All rights reserved.
http://dx.doi.org/10.1016/j.arth.2014.02.028
Contents lists available at ScienceDirect
The Journal of Arthroplasty
journal homepage: www.arthroplastyjournal.org
Please cite this article as: Courtney PM, et al, Predictors of the Need for Critical Care After Total Joint Arthroplasty: An Update of Our
Institutional Risk Stratification Model, J Arthroplasty (2014), http://dx.doi.org/10.1016/j.arth.2014.02.028