Downloaded from http://journals.tums.ac.ir/ on Thursday, January 24, 2013 Copyright© 2012, IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY. All rights reserved. 175 ORIGINAL ARTICLE Iran J Allergy Asthma Immunol June 2012; 11(2): 175-181. Efficacy of Sublingual Swallow Immunotherapy in Children with Rye Grass Pollen Allergic Rhinitis: A Double-blind Placebo-Controlled Study Akefeh Ahmadiafshar 1,2 , Mina Maarefvand 1 , Babak Taymourzade 1 , Saeedeh Mazloomzadeh 2,3 , and Zohreh Torabi 1 1 Department of Pediatrics, Aayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran. 2 Metabolic Research Center of Zanjan University of Medical Sciences 3 Department of Medical Statistics, Medical Faculty, Zanjan University of Medical Sciences, Zanjan, Iran                  ABSTRACT                                                       !"#                     $       %                               &  ’  (  )          *"     +,, -      "%   +,,          .                          !             )              / 0 / 0 10  INTRODUCTION Allergy is common problem in the world. It is a chronic condition and affect on patients’ quality of life, work productivity and expenditure. 1 Determination of environmental allergens, allergen avoidance and medication sometimes are beneficial and could control these disorders. Corresponding Author: Akefeh Ahmadiafshar, MD; Department of Pediatrics, Sub-specialist in Immunology and Allergy, Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran. Tel : (+98 241) 4223 095, Fax: (+98 241) 4131 340, E-mail: akefeh45@zums.ac.ir, zu_afshar@yahoo.com