_____________________________________________________________________________________________________ *Corresponding author: E-mail: ddamuliragab@yahoo.co.uk; American Journal of Experimental Agriculture 9(2): 1-12, 2015, Article no.AJEA.17833 ISSN: 2231-0606 SCIENCEDOMAIN international www.sciencedomain.org Gene Pyramiding Improved Resistance to Angular Leaf Spot in Common Bean G. Ddamulira 1* , C. Mukankusi 2 , M. Ochwo-Ssemakula 1 , R. Edema 1 , P. Sseruwagi 3 and P. Gepts 4 1 Department of Agricultural Production, Makerere University Kampala, Uganda. 2 International Centre for Tropical Agriculture, P.O.Box 6247, Kampala, Uganda. 3 Mikocheni Agricultural Research Institute, P.O.Box 6226, Dar es salaam, Tanzania. 4 Department of Plant Sciences, University of California, 1 shields avenue, Davis, CA 95616, USA. Authors’ contributions This work was carried out in collaboration between all authors. Authors CM and MOS designed the study, wrote the protocol and wrote the first draft of the manuscript. Authors RE, PS and PG reviewed the experimental design and all the drafts of the manuscript. Author GD managed the analyses of the study. Author CM identified the plants. Authors GD and PG performed the statistical analyses. All authors read and approved the final manuscript. Article Information DOI: 10.9734/AJEA/2015/17833 Editor(s): (1) Sławomir Borek, Department of Plant Physiology, Adam Mickiewicz University, Poland. Reviewers: (1) Edward Missanjo, Malawi College of Forestry and Wildlife, Malawi. (2) Klára Kosová, Crop Research Institute, Prague, Czech Republic. Complete Peer review History: http://sciencedomain.org/review-history/10298 Received 27 th March 2015 Accepted 29 th April 2015 Published 24 th July 2015 ABSTRACT Aims: The study was conducted to determine the effectiveness of pyramided genes in improving angular leaf spot (ALS) resistance in susceptible common bean cultivars. Study Design: The experiment was set in randomized block design with three replications. Place and Duration of Study: The experiment was conducted at International Centre for Tropical Agriculture (CIAT) at Kawanda, Uganda in 2010-2014. Methodology: Crosses among three Pseudocercospora griseola resistant lines of common bean (Phaseolus vulgaris) were developed. The crosses involved five inbred lines, AND277, Mexico 54, G5686 and two susceptible cultivars, K132 and Kanyebwa. The resistant lines were crossed in cascading pyramiding scheme to develop triple crosses (TC). The TC F 1 and each of the resistant parents were crossed with each of the two susceptible cultivars to generate four parent crosses Original Research Article