ORIGINAL PAPER Determination of optimal viewing regions for X-ray coronary angiography based on a quantitative analysis of 3D reconstructed models Joel A. Garcia Æ Babak Movassaghi Æ Ivan P. Casserly Æ Andrew J. Klein Æ S.-Y. James Chen Æ John C. Messenger Æ Adam Hansgen Æ Onno Wink Æ Bertron M. Groves Æ John D. Carroll Received: 17 January 2008 / Accepted: 4 December 2008 / Published online: 20 December 2008 Ó Springer Science+Business Media, B.V. 2008 Abstract Current expert-recommended views for coronary angiography are based on heuristic experi- ence and have not been scientifically studied. We sought to identify optimal viewing regions for first and second order vessel segments of the coronary arteries that provide optimal diagnostic value in terms of minimizing vessel foreshortening and overlap. Using orthogonal 2D images of the coronary tree, 3D models were created from which patient-specific optimal view maps (OVM) allowing quantitative assessment of vessel foreshortening and overlap were generated. Using a novel methodology that averages 3D-based optimal projection geometries, a universal OVM was created for each individual coronary vessel segment that minimized both vessel foreshortening and overlap. A universal OVM model for each coronary segment was generated based on data from 137 patients undergoing coronary angiography. We identified viewing regions for each vessel segment achieving a mean vessel foreshortening value of 5.8 ± 3.9% for the left coronary artery (LCA) and 5.6 ± 3.6% for the right coronary artery (RCA). The overall mean overlap values achieved were 8.7 ± 7.9% for the LCA and 4.6 ± 3.2% for the RCA. This scientifically-based OVM evaluation of coronary vessel segments provides the means to facilitate acquisitions during coronary angiography and interventions that minimize imaging inaccuracies related to foreshortening and overlap, improving the accuracy, efficiency, and safety of diagnostic and interventional coronary procedures. Keywords Angiography  Imaging  Radiography  Optimal view map, coronary  Three-dimensional Introduction Standardized views are typically employed by most operators to visualize coronary segments of interest during diagnostic and interventional coronary procedures. These views are based on expert recom- mendations [1–5] or the experience of the individual J. A. Garcia Denver Health Medical Center, 777 Bannock St., Denver, CO 80204, USA J. A. Garcia (&)  I. P. Casserly  A. J. Klein  S.-Y.James Chen  J. C. Messenger  A. Hansgen  B. M. Groves  J. D. Carroll Division of Cardiology, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Box B-132, Denver, CO 80262, USA e-mail: joel.garcia@dhha.org B. Movassaghi  O. Wink Philips Medical Systems (PMS), Clinical Research, Denver, CO, USA I. P. Casserly Division of Cardiology, Denver VA Medical Center, 1055 Clermont Street, Denver, CO 80220, USA 123 Int J Cardiovasc Imaging (2009) 25:455–462 DOI 10.1007/s10554-008-9402-5