_____________________________________________________________________________________________________ *Corresponding author: E-mail: subhashkothiyal@gmail.com; British Journal of Pharmaceutical Research 12(4): 1-5, 2016, Article no.BJPR.25727 ISSN: 2231-2919, NLM ID: 101631759 SCIENCEDOMAIN international www.sciencedomain.org Evaluation of the Anti-Inflammatory Activity of the Methanolic Extract of the Fruits of Ficus palmata Subhash Chandra 1* and Sarla Saklani 1 1 Department of Pharmaceutical Chemistry, H. N. B. Garhwal University (A Central University), Srinagar Garhwal, Uttarakhand, 246174, India. Authors’ contributions This work was carried out in collaboration between both authors. Author SC designed the study, performed the statistical analysis, wrote the protocol and wrote the first draft of the manuscript. Author SS managed the analyses of the study. Author SC managed the literature searches. Both authors read and approved the final manuscript. Article Information DOI: 10.9734/BJPR/2016/25727 Editor(s): (1) Dongdong Wang, Department of Pharmacogonosy, West China College of Pharmacy, Sichuan University, China. (2) Ke-He Ruan, Director of the Center for Experimental Therapeutics and Pharmacoinformatics (CETP)Professor of Medicinal Chemistry & Pharmacology, Department of Pharmacological and Pharmaceutical Sciences, University of Houston, USA. Reviewers: (1) A. Veerareddy, Suven Life Sciences Ltd., Hyderabad, India. (2) Leonor Thomson, Universidad de la República, Uruguay. (3) Nuhu Sambo, Bingham University, Nigeria. (4) Ravendra Singh, Rutgers University, USA. (5) Yonghua Wang, Northwest A&F University, Shaanxi, China. Complete Peer review History: http://sciencedomain.org/review-history/15426 Received 17 th March 2016 Accepted 1 st June 2016 Published 19 th July 2016 ABSTRACT Aim: This study was aimed to evaluate the possible in vivo anti-inflammatory activity of the methanolic extract of fruits of Ficus palmata. Place and Duration of the Study: In vivo studies were carried out in the Animal House of the S.B.S Ballawala Dehradun, Uttarakhand, India, between December 2014 and March 2015). Study Design: Three different doses of methanolic extract were tested in this study regarding their anti-inflammatory activity. Methodology: In vivo studies of anti-inflammatory effects of feeding adult albino rats under investigation with three different doses (50, 100 and 150 mg/kg -1 ) of methanolic extract were carried out after 24 hours of inducing inflammation by injecting investigated animals with carrageen. Results: The results of anti inflammatory activity study showed that the fruit extracts at doses of 50, 100 and 150 mg/mL inhibited carrageenan induced paw edema in rats. The percent inhibition Original Research Article