L etter to the Editor Uveal melanoma in an 18-year-old African black man Joe¨ l Gambrelle, 1,2 Guila Dayan, 1 Loris G. Baggetto, 1 Mojgan Devouassoux- Shisheboran, 3 Monique Salle, 3 Ste´phane Labialle, 1 Landry Gayet, 1 Ste´phane Barakat, 1 Laurent Kodjikian 2 and Jean-Daniel Grange 2 1 Institut de Biologie et chimiedes prot, Unite` Mixte de Recherche 5086 centre National de la Recherche scientifique, Lyons, France 2 Department of Ophthalmology, Croix-Rousse Hospital, Lyons, France 3 Department of Anatomy and Pathological Cytology, Croix-Rousse Hospital, Lyons, France doi: 10.1111/j.1600-0420.2004.00386.x Sir, U veal melanoma is the most fre- quently occurring intraocular tumour in the white population. Occur- rence increases with age and peaks between the sixth and seventh decades. In contrast, this tumour occurs rarely A C D B Fig. 1. Clinical and microscopic aspects. (A) Eye fundus showing a mushroom-shaped melanoma with retinal effraction (arrowheads). (B) Fine-needle aspiration cytology showing melanogenic epithelioid cells. MayGru¨nwaldGiemsa; original magnification 250. (C) Enucleation: entirely necrotic malignant melanoma. Haematoxylin phloxin safran; original magnification 25. (D) Enucleation: tumour necrosis showing melanic pigment and melanophages without any preserved cells. Haematoxylin phloxin safran; original magnification 400. ACTA OPHTHALMOLOGICA SCANDINAVICA 2005 134