Methods Research Report Reliability Testing of the AHRQ EPC Approach to Grading the Strength of Evidence in Comparative Effectiveness Reviews Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD 20850 www.ahrq.gov Contract No. 290-2007-10056-I Prepared by: RTI International–University of North Carolina Evidence-based Practice Center Research Triangle Park, NC Investigators: Nancy D. Berkman, Ph.D. Kathleen N. Lohr, Ph.D. Laura C. Morgan, M.A. Emily Richmond, M.P.H Tzy-Mey Kuo, Ph.D, M.P.H. Sally Morton, Ph.D. Meera Viswanathan, Ph.D. Douglas Kamerow, M.D. Sue West, Ph.D. Elizabeth Tant, B.A. AHRQ Publication No. 12-EHC067-EF May 2012