Ambulatory treatment of fast breathing in young infants aged under 60 days: a double-blind, randomized, placebo-controlled equivalence trial in low-income settlements of Karachi Shiyam S Tikmani 1* , Amber A Muhammad 1 , Yasir Shafiq 1 , Saima Shah 1 , Naresh Kumar 1 , Imran Ahmed 1 , Iqbal Azam 2 , Omrana Pasha 2 , Anita KM Zaidi 1 1 Department of Paediatrics and Child health, Aga Khan University, Karachi, Pakistan 2 Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan Corresponding author: Shiyam Sunder Tikmani Instructor, Department of Community Health Sciences, Aga Khan University Karachi. e-mail: shiyam.sunder@aku.edu or shiyam.s.tikmani@gmail.com Summary: This trial failed to show the equivalence of placebo to amoxicillin in term young infants under 2 months of age with isolated fast breathing who did not have other clinical signs of illness or hypoxemia, and were managed in primary care settings. Running title: Ambulatory treatment of fast breathing in young infants © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com Clinical Infectious Diseases Advance Access published October 19, 2016 by guest on October 20, 2016 http://cid.oxfordjournals.org/ Downloaded from