CHAPTER 23 Development of Marine Probiotics: Prospects and Approach Se-Kwon Kim,* ,†,1 Ira Bhatnagar,* ,† and Kyong-Hwa Kang † Contents I. Introduction 354 II. Prerequisites for Probiotics 355 III. Potential of Probiotics 356 IV. Approaches for Development of Marine Probiotics 358 V. Conclusion 359 References 360 Abstract The term probiotics stands for bacterial strain acting for the uplift- ment of beneficial gut microflora as well as restricting the growth of decay or disease causing bacteria and other agents. They protect us from disease causing microorganisms and are vital for the diges- tion of nutrients and food. Researchers are now trying to explore the possibilities of therapeutic applications of probiotics in inflam- matory bowel disease, treating diarrhea, eczema prevention in children, and reducing bladder cancer recurrence and urinary tract infections. The best known probiotic strains are Bifidobacteria, Lactobacilli, and Streptococcus thermophilus and can be found in food products such as yoghurts, fermented and unfermented milk, miso, tempeh, and some juices and soy beverages. Thus, as a substitute to the use of antibiotics, the dietary supplementation Advances in Food and Nutrition Research, Volume 65 # 2012 Elsevier Inc. ISSN 1043-4526, DOI: 10.1016/B978-0-12-416003-3.00023-8 All rights reserved. * Department of Chemistry, Pukyong National University, Busan, Republic of Korea { Marine Bioprocess Research Center, Pukyong National University, Busan, Republic of Korea 1 Corresponding author: Se-Kwon Kim, E-mail address: sknkim@pknu.ac.kr 353