ABSTRACTS Heart, Lung and Circulation 53 2011;20:35–67 Abstracts POSTER PRESENTATIONS Outcomes after Mitral and Aortic Valve Replacement Surgery: Comparison and Predictors Mahmoon Shirzad ∗ , Abbasali Karimi, Seyed Hossein Ahmadi, Samaneh Dowlatshahi, Saeed Davoodi, Mehrab Marzban Tehran Heart Center, Iran Keywords: In-hospital mortality; Heart valve disease; Valve surgery; Valve dysfunction Objectives: Since Heart valve surgery is the second most common type of cardiac surgery, and there is limited infor- mation about the outcomes associated to these types of surgeries, predictors of these complications, and compar- ison between aortic and mitral replacement procedures as being two most common valve surgeries, we conducted the present investigation to compare between aortic and mitral valve replacement in preoperative risk factors and in hospital mortality and morbidities. Methods: A total of 709 patients who had undergone pure mitral and aortic valve replacement over a 5 year period were enrolled in the study. Patient demographics and risk factors, operative information and postopera- tive outcomes data were extracted from our computerised surgery data base, and a comparison between aortic and mitral valve replacement was done retrospectively. Results: There was no significant difference between our two groups in mortality rate, infectious, ischaemic, and pulmonary complications while cardiac complications were significantly more prevalent in mitral valve replace- ment. After adjustment for confounder preoperative risk factors, which could affect post operation mortality and morbidities, we found still significantly higher post oper- ative cardiac complications in mitral valve replacement group (OR: 2.415, CI = 1.527–3.819, p = 0.0002). Conclusion: Although we found that cardiac complica- tions after mitral valve replacement are higher than aortic valve replacement significantly, there was no significant difference between these two procedures in other compli- cations and in hospital mortality, so there should be focus on minimising cardiac complications and improving pro- cesses of care that would enable complications to be better resolved if they occur. doi:10.1016/j.hlc.2010.10.040 Clopridogel as an Alternative Therapy after Biological Aortic Valve Replacement (BAVR) P. Poslussny ∗ , S. Folkmann, M.L. Harrer, G. Weiss, B. Heine, M. Grabenwoeger Departement of Cardiovascular Surgery, KH Hietzing, Vienna, Austria Background: After aortic valve replacement using a tis- sue valve, patients are treated with Coumadin/warfarin for 3 months. Is sinus rhythm is evident, therapy is changed to 100mg of salicyl acid (ASA) a. day. These are the STS,ACC/AHA guidelines. Clopridogel is well known in cardiology after coronary stenting and also in peripheral vascular surgery. Methods: In our 3-years retrospective analysis 130 patients were treated with clopridogel after biological valve replacement (BAVR). The therapy started on the fifth day after surgery and ended after 3 months. All patients underwent echocardiography before dismission and after 3 months. Results: In our study group we could not detect any signs of thromembolic complications or neurological dis- orders. We found regular function of the valve prosthesis in all cases. One patient had to be re-operated cause of endocarditis of the prosthesis and died after prolonged ventilation problems. In the control group (277 patients) we found two cases of intracerebral haemorrhagia, which was caused to death. Both of them were older than 80 years. Conclusions: In the last years the clinical use of tissue valves has increased because of longer durability. Many post-operative regimes have been described. Clopridogel 75 mg/day is an excellent alternative therapy after biolog- ical aortic valve replacement. We all know the compliance of elder patients after cardiac surgery. So we have an easy treatment for this group of patients. doi:10.1016/j.hlc.2010.10.041 Is There a Real Benefit to Dialysis Patients Undergoing Cardiac Surgery? H. Jayasekera ∗ , A. Wood, R. Griffin, N. Pinto, J. Mundy, P. Shah Cardiothoracic, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia Purpose: The study evaluates the short term outcomes, long term survival and quality of life of dialysis patients undergoing cardiac surgery. Methods: The study period was February 1999 to November 2008. Study is in two parts, A and B. Part A: compares the short term outcomes of three groups (X, Y, Z) undergoing primary CABG i.e. primary CABG with cre- atinine < 2 mol/l (X: 3947/4050), creatinine > 2 (Y: 87/4050) and on Dialysis (Z: 16/4050). Part B: evaluates the outcomes of all dialysis patients undergoing cardiac surgery i.e. 45 patients (53% CABG, 25% AVR). The mean age was 59.9 and sex ratio (M:F) of 32/13. 5 patients received surgery as a part of renal transplant work up. Forty-one variables were studied to define predictors. The mean follow up period was 41.8 months. Follow up was 100% (18/18). Their func- tional class and quality of life was assessed by telephone interviews. Results: Part A: The significant difference between the groups (Z > Y > X) in short term outcome were blood prod- uct usage (p = 0.007), post op AMI (p = 0.002), pulmonary (p = < 0.001), infection (p < 0.001) and death (p < 0.001). Part B: The 30 day mortality of the dialysis patients was 6/45(13.3%) and late death was 21/45 (46.6%). Significant predictors are described in Table 1. NYHA class was I-II