Article Title Page RFID in Healthcare: A Six Sigma DMAIC and Simulation Case Study Author Details Peter B. Southard Opus College of Business, University of St. Thomas, St. Paul, MN, USA Charu Chandra Department of Management Studies, University of Michigan, Dearborn, MI, USA Sameer Kumar Opus College of Business, University of St. Thomas, Minneapolis, MN, USA Corresponding author: Sameer Kumar Corresponding Author’s Email: skumar@stthomas.edu Structured Abstract Purpose: Develop a business model to generate quantitative evidence of the benefits of implementing Radio Frequency Identification (RFID) technology limiting the scope to outpatient surgical processes in hospitals. Design/Methodology/Approach: The study primarily uses the Define, Measure, Analyze, Improve, and Control (DMAIC) approach and draws on various analytical tools such as work flow diagrams, value stream mapping, and discrete event simulation to examine the effect of implementing RFID technology on improving effectiveness (quality and timeliness) and efficiency (cost reduction) of outpatient surgical processes. Findings: Analysis showed significant estimated annual cost and time savings in carrying out patients’ surgical procedures with RFID technology implementation for the outpatient surgery processes in a hospital. This is largely due to elimination of both the non-value added activities of locating supplies and equipment and also the elimination of the “return” loop created by preventable post operative infections. Several poka-yokes developed using RFID technology were identified to eliminate those two issues, as well as, for improving the safety of the patient and cost effectiveness of the operation to ensure the success of the outpatient surgical process. Practical implications: Several poka-yokes developed using RFID technology were identified for improving the safety of the patient and cost effectiveness of the operation to ensure the success of the outpatient surgical process. Originality/value: Many stakeholders in the hospital environment will be impacted including patients, physicians, nurses, technicians, administrators and other hospital personnel. Different levels of training of hospital personnel will be required, based on the degree of interaction with the RFID system. Computations of costs and savings will help decision makers understand the benefits and implications of the technology in the hospital environment. Keywords: Business Process Re-engineering/Patient Focused Care, Six Sigma, Continuous Quality Improvement, Patient safety, PDCA