Short report Antinociceptive activity of Ceriops decandra leaf and pneumatophore S.J. Uddin * , J.A. Shilpi, J. Barua, R. Rouf Phytochemistry and Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh Received 22 December 2003; accepted 14 December 2004 Abstract The ethanol extract of Ceriops decandra leaf and pneumatophore, at the oral doses of 250 and 500 mg/kg, showed a dose-dependent and significant inhibition of acetic acid-induced writhing in mice. On the contrary, the bark extract was devoid of any significant activity. D 2005 Elsevier B.V. All rights reserved. Keywords: Ceriops decandra; Antinociceptive activity 1. Plant Ceriops decandra syn. Ceriops candolleana Arn. (Rhizophoraceae), glabrous shrub or small tree, was collected from the Sundarban mangrove forest located at the South-Eastern part of the delta region in Khulna district in November 2003 and taxonomically identified by Prof. Abdul Matin, Forestry Discipline, Khulna University. 2. Uses in traditional medicine and reported activities The whole plant is astringent. The bark is used to stop haemorrhage and applied to malignant ulcer [1]. People living in the coastal regions of the Sundarban use the leaf in 0367-326X/$ - see front matter D 2005 Elsevier B.V. All rights reserved. doi:10.1016/j.fitote.2004.12.015 * Corresponding author. E-mail address: uddinsj@yahoo.com (S.J. Uddin). Fitoterapia 76 (2005) 261 – 263 www.elsevier.com/locate/fitote