International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Vol. 4, Issue 2, pp: (421-426), Month: October 2016 - March 2017, Available at: www.researchpublish.com Page | 421 Research Publish Journals Prevalence of Antibiotic Misuse among Jazan University Students Abu Obaida Yassin 1 , Nouf Al-Essa 2 , Rafan Madkor 2 , Amany Mashi 2 , Tahani jubaili 2 , Arwa Abutaleb 2 , Rbuoah Ayashi 2 1 Assistant Professor, Department of Internal Medicine Faculty of Medicine, Jazan University, Jazan, Saudi Arabia 2 Intern, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia Abstract: An antibiotic is a drug that kills or slows the growth of bacteria. Antibiotics have wide variety of uses but still their misuse can lead to resistance towards wide range of pathogens and bacteria. This may lead to face new set of threats to public health so the rational prescription of antibiotics has become a central focus of professional and public health measures to fight the spread of resistant organisms. Objective: The study conductedto assess the awareness of Jazan University students about antibiotics use by evaluation of prevalence of antibiotic use with common colds. Method: A cross sectional study conduct in Jazan University conducted in medical and non-medical, all student males and females are included. The Sample size was 440 and the data collected by the non-structure self-admitted questionnaire and analyzed in SPSS program. Result: The number of students studied was 440 the males was 49. 8% and the females was 50. 2%. thepercent of medical students 50. 2% and the percent of non-medical students 49. 8%. the study showed there is significant difference in antibiotic use with common cold between medical and non-medical students 48. 9%, 59. 4% respectively. The major causes for this use is common cold by 56. 4 % among other causes. Conclusion: This study found antibiotic use with common cold is high among Jazan University student. There is no different in gender, social status and residence in antibiotic missus on other ways the effect of education leading to different between medical and non-medical student. Keywords: Antibiotics, misuse, Resistance; Prescription. 1. INTRODUCTION An antibiotic is a drug that kills or slows the growth of bacteria. Antibiotics are one class of antimicrobials, a larger group which also includes anti-viral, anti-fungal, and anti-parasitic drugs. Antibiotics are chemicals produced by or derived from microorganisms (i. e. bugs or germs such as bacteria and fungi). The first antibiotic was discovered by Alexander Fleming in 1928 in a significant breakthrough for medical science. Antibiotics are among the most frequently prescribed medications in modern medicine. Some antibiotics are 'bactericidal', meaning that they work by killing bacteria. Other antibiotics are 'bacteriostatic', meaning that they work by stopping bacteria multiplying. Each different type of antibiotic affects different bacteria in different ways. For example, an antibiotic might inhibit a bacterium's ability to turn glucose into energy, or its ability to construct its cell wall. When this happens, the bacterium dies instead of reproducing. Some antibiotics can be used to treat a wide range of infections and are known as 'broad-spectrum' antibiotics. Others are only effective against a few types of bacteria and are called 'narrow-spectrum' antibiotics. Antibiotics have wide variety of uses but still their misuse can lead to resistance towards wide range of pathogens and bacteria. This may lead to face new set of threats to public health [1]. World Health Organization (WHO) defines the Antimicrobial resistance (AMR) as “the resistance of a microorganism to an antimicrobial agent to which it was originally sensitive”. [2]. The Antibiotics is given in 68% of acute respiratory tract cases and the 80% of these according to disease control center (CDC) guidelines were unnecessary. The annual spent on