CASE REPORT
250 Case Reports Heart, Lung and Circulation
2008;17:243–263
4. Holstege C, Baer A, Brady WJ. The electrocardiographic tox-
idrome: the ECG presentation of hydrofluoric acid ingestion.
Am J Emerg Med 2005;23(2):171–6.
5. Cordero SC, Goodhue WW, Splichal EM, Kalasinsky VF. A
fatalitiy due to ingestion of hydrofluoric acid. J Anal Toxicol
2004;28:211–3.
6. Singal PK, Iliskovic N. Doxorubicin-induced cardiomyopathy.
N Engl J Med 1998;339(13):900–5.
7. Fernandez-Sola J, Estruch R, Grau JM, Pance JC, Rubin E,
Urbano-Marquez A. The relation of alcoholic myopathy to car-
diomyopathy. Ann Intern Med 1994;120:529–36.
Percutaneous Closure of Left Ventricular Free Wall
Rupture with Associated False Aneurysm to
Prevent Cardioembolic Stroke
Wil Harrison, MBChB
a,∗
, Peter N. Ruygrok, FRACP
a
, Sally Greaves, FRACP
a
,
Namal Wijesinghe, MD, MRCP
b
, Hamish Charleson, FCSANZ
b
and
Clyde Wade, FRACP
b
Gerard Devlin, FRACP
b
a
Greenlane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
b
Department of Cardiology, Waikato Hospital, Hamilton, New Zealand
Left ventricular (LV) false aneurysm is an uncommon complication of myocardial infarction. Conventional treatment
mandates surgical repair but is associated with significant perioperative risk. We present a case of successful percutaneous
closure of a LV false aneurysm in a patient at high operative risk who suffered cardioembolic stroke related to thrombus
within the aneurysm. The primary aim of treatment was to prevent recurrent embolic event.
(Heart, Lung and Circulation 2008;17:243–263)
© 2007 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and
New Zealand. Published by Elsevier Inc. All rights reserved.
Keywords. Left ventricular false aneurysm; Percutaneous closure; Stroke; Amplatzer
Introduction
L
eft ventricular (LV) false aneurysm formation occurs
when a rupture in the myocardium is contained by
pericardium or scar tissue.
1
The largest reported series
of 290 patients identified myocardial infarction (MI) as
the most common cause, responsible for just over half
of all cases.
2
In this setting, false aneurysm was twice as
common with inferior compared to anterior infarcts. The
reason for this predilection is uncertain but could be due to
the higher likelihood of anterior LV wall rupture to result in
haemopericardium and death.
3
Previous cardiac surgery
accounts for a third of cases, mitral valve replacement
being the most common antecedent procedure. Trauma,
infection and previous cardiac catheterisation
4
have also
been implicated.
The risk of false aneurysm rupture if left untreated
is between 30% and 50%.
2,5,6
Conventional management
Received 27 November 2006; received in revised form 17 April
2007; accepted 18 April 2007; available online 11 September 2007
∗
Corresponding author at: Greenlane Cardiovascular Service,
Level 3 Auckland City Hospital, Private Bag 92-024, Auckland 1,
New Zealand. Tel.: +64 9 307 4949; fax: +64 9 307 4950.
E-mail address: wharriso@middlemore.co.nz (W. Harrison).
is with surgical repair, but this procedure has an asso-
ciated mortality of approximately 23%.
2
The advent of
percutaneous closure devices provides an alternative
management option in those patients who are haemody-
namically stable but at high operative risk.
We present a case of successful percutaneous closure
of a LV false aneurysm in a patient at high operative risk
who suffered cardioembolic stroke related to thrombus
within the aneurysm. The primary aim of treatment was to
prevent recurrent embolic event, the secondary objective
being to reduce the risk of aneurysm rupture.
Case History
A 47-year-old Caucasian female presented to hospital with
an acutely ischaemic right leg caused by femoral artery
thrombus. Embolectomy was successfully performed.
At this time electrocardiographic evidence of previous
inferior MI was established. Transthoracic echocardio-
gram (TTE) showed thinning and akinesis of the basal
inferior LV wall and coronary angiography showed an
occluded mid-right coronary artery. The aetiology of the
embolism was presumed to be mural thrombus. She was
treated medically, which included anticoagulation with
warfarin.
© 2007 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of
Australia and New Zealand. Published by Elsevier Inc. All rights reserved.
1443-9506/04/$30.00
doi:10.1016/j.hlc.2007.04.009