Signal-to-Noise Ratio and Absorbed Power as Functions of Main Magnetic Field Strength, and Definition of “90°” RF Pulse for the Head in the Birdcage Coil Christopher M. Collins 1,3 and Michael B. Smith 1,2 * Calculations of the RF magnetic (B 1 ) field as a function of frequency between 64 and 345 MHz were performed for a head model in an idealized birdcage coil. Absorbed power (P abs ) and SNR were calculated at each frequency with three different methods of defining excitation pulse amplitude: maintaining 90° flip angle at the coil center (center /2), maximizing FID amplitude (Max. A FID ), and maximizing total signal amplitude in a reconstructed image (Max. A image ). For center /2 and Max. A image , SNR increases linearly with increasing field strength until 260 MHz, where it begins to increase at a greater rate. For these two methods, P abs increases continually, but at a lower rate at higher field strengths. Above 215 MHz in MRI of the human head, the use of FID amplitude to set B 1 excitation pulses may result in apparent decreases in SNR and power requirements with increasing static field strength. Magn Re- son Med 45:684 – 691, 2001. © 2001 Wiley-Liss, Inc. Key words: calculations; SNR; power; MRI; high field Predictions of trends in signal-to-noise ratio (SNR) and specific energy absorption rate (SAR) with increasing static magnetic field (B 0 ) strength based on MR theory, the principle of reciprocity, and analytical RF magnetic field (B 1 ) calculations have been shown to be reasonably accu- rate at frequencies up to 64 MHz in head- and body-sized samples (1,2). MRI experiments are currently performed at static magnetic field (B 0 ) strengths as high as 8.0 Tesla, where the frequency of the RF magnetic field (B 1 ) for imaging with 1 H is about 340 MHz. At these frequencies, significant interaction between the applied B 1 field and human tissues is expected. The effects of this interaction on SNR and the total absorbed power are complicated, and are dependent on the experiment being performed, RF coil type and performance, and even on the specific subject geometry and position in the coil (2,3). In this study we performed calculations of SAR in the head, the total absorbed power (P abs ) in the head and shoulders, and SNR on an axial plane of the head at several B 1 frequencies between 64 and 345 MHz for an anatomi- cally-accurate model in an idealized birdcage coil. The head position and orientation, and the coil behavior are kept constant so that B 1 frequency and definition of the excitation pulse are the only variables. Electrical proper- ties of all tissues are set appropriately at each frequency. The excitation pulse amplitude is defined with three dif- ferent methods at each frequency. Since our interest was primarily in the effects of the high-frequency RF fields on the imaging experiment, we chose to ignore several factors that complicated both the calculation and interpretation of the results. We chose to consider signal from protons in water only, and to ignore T 1 and T 2 relaxation effects in this work. This simplifies the presentation of results, making them independent of TE and TR, but it also removes some realism from the simulation. We also neglected many other experimental effects, such as those of B 0 inhomogeneity, inevitable vari- ation in sample and coil geometry, signal filtering, and signal amplifier integrity and performance (4). Thus, the findings concerning signal in the images, FID amplitude, and SNR presented here should be considered predictions of the types of phenomena that may be seen at high fre- quency due to behavior of the RF fields. Manifestation of these phenomena in experiment should not be expected to occur exactly as in these calculations. METHODS The finite difference time domain (FDTD) numerical method for electromagnetics was used to calculate all elec- trical and magnetic fields throughout a head model in an idealized birdcage coil. This method of calculation has previously been described in the literature (5,6). Here we present our methods for modeling the MR experiment with the FDTD method, and then relate the calculated results to the MR experiment. Head Model A model of the human head for use with the FDTD method was created by first segmenting 120 digital photographic images of axial slices through a male cadaver from the National Library of Medicine’s Visible Human Project into 20 materials (18 tissues, one free space, and one metal dental filling), and then transforming these segmented im- ages into a 3D grid of Yee cell cubes. One computer pro- gram was written to perform the transformation, and an- other was written to ensure the continuity of skin on the outer surface of the model. Segmentation was performed manually with reference to textbooks on anatomy and with assistance from two practicing radiologists. At each fre- quency, appropriate values from the literature for tissue mass density (7–10), water content by percent mass (11), and electrical permittivity and conductivity (12) were as- signed to each tissue. Tissue mass density information was 1 Department of Radiology, Pennsylvania State University College of Medi- cine, Hershey, Pennsylvania. 2 Department of Cellular and Molecular Physiology, Pennsylvania State Uni- versity College of Medicine, Hershey, Pennsylvania. 3 Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania. *Correspondence to: Michael B. Smith, Center for NMR Research, NMR/MRI Building, Department of Radiology H066, Pennsylvania State University Col- lege of Medicine, 500 University Drive, Hershey, PA 17033. E-mail: mbsmith@psu.edu Received 22 March 2000; revised 2 November 2000; accepted 6 November 2000. Magnetic Resonance in Medicine 45:684 – 691 (2001) © 2001 Wiley-Liss, Inc. 684