Role of Endothelium-Derived CC Chemokine Ligand 2 in Idiopathic Pulmonary Arterial Hypertension Olivier Sanchez*, Elisabeth Marcos*, Frédéric Perros #, Elie Fadel §, Ly Tu*, Marc Humbert #, Philippe Dartevelle#, Gerald Simonneau§, Serge Adnot*, Saadia Eddahibi* * INSERM U841 and Département de Physiologie Explorations Fonctionnelles, Hôpital H. Mondor, AP-HP, 94010, Créteil, France # INSERM U764, UPRES EA2705, Service de Pneumologie, Centre National de Référence de l’Hypertension Artérielle Pulmonaire, Hôpital Antoine-Béclère, Assistance-Publique Hôpitaux de Paris, Université Paris-Sud 11, Clamart, France § UPRES EA2705, Service de Chirurgie Thoracique, Vasculaire et de Transplantation Cardiopulmonaire, Hôpital Marie Lannelongue, Le Plessis Robinson, 92, France Correspondence: Saadia Eddahibi INSERM U841, Faculté de Médecine 8, avenue Général Sarrail, 94010 Créteil, France Tel : 33 1 48 98 17 77 Fax: 33 1 48 98 17 77 E-mail: eddahibi@im3.inserm.fr Running title: CCL2 in Idiopathic Pulmonary Arterial Hypertension Key words: Pulmonary hypertension, endothelial cells, smooth muscle cells, chemokines, CCL2 AJRCCM Articles in Press. Published on September 6, 2007 as doi:10.1164/rccm.200610-1559OC Copyright (C) 2007 by the American Thoracic Society. "This article has an online data supplement, which is accessible from this issue's table of content online at www.atsjournals.org"