2006. Age distribution: 14-68 years. Etiol- ogy: Trauma 20/73(27.39%), Balanitis Xe- rotica Obliterans 2/73(2.73%), Iatrogenic 26/73(35.61%), Infection 3/73(4.10%), Idiopathic 22/73(30.13%). Site: Penobul- bar–25/73, Bulbar-38/73, Membranous- 8/73 and Full length-2/73. Suprapubic catheter was inserted preoperatively: 21/73 patients. Preputial / distal penile skin was used in all patients. Buccal mu- cosa was not used in any patient. Hospi- talization was for 4-5 days. Catheter was removed after 21 days. All patients had their first endoscopic checkup after 3 months. Subsequently, they were followed up by uroflometry. Routine imaging of urethra for follow up was not carried out. Results: 63/73 (86.30%) patients had sat- isfactory outcome not requiring any fur- ther treatment. 8/73 (10.95%) patients developed anastomotic stricture, 3/8 opti- cal internal urethrotomy, 5/8 dilatation alone, 2/73 (2.75%) external meatal steno- sis. None had urinary fistula and required repeated urethroplasty. Follow up ranged from 3 months to 8 years. Conclusions: Dorsal onlay urethroplasty using preputial/distal penile skin is a satis- factory procedure. Preputial/distal penile skin is devoid of hair and fat and hence, is an ideal graft material. Even in circum- cised patients, distal penile skin can be harvested. Long-term follow up is required in judging results of patients with stric- ture urethra. MP-21.15 (Podium) The protective effect of erythropoietin on seminiferous tubules damage in rat testicular torsion model Purnomo BB, Setiadi A Department of Urology Saiful Anwar General Hospital, Malang, Indonesia Introduction: Testicular torsion is an acute spermatic cord twist that need emergency detorsion. Delayed manage- ment will lead to infarct or testicular dam- age, infertility, and risk of testicular lost due to ischemic hypoxia, inflammation, and apoptosis. Previous studies show the benefit of erythropoietin as a tissue pro- tective agent by improves blood circula- tion, stimulates angiogenesis, altered in- flammation and apoptosis process. The aim of this study is prove that erythropoi- etin has testoprotective effect in testicular torsion. Material & Methods: Fifteen (10-12 week, 150-200 grams) male Sprague-Daw- ley rats were divided into three equal groups. Group 1 underwent a sham opera- tion of the right testis under general an- aesthesia. Group 2 underwent a similar operation but the right testis was rotated 720° clockwise, maintained by fixing the testis to the scrotum for 60 minutes, fol- lowed by rerotated (retorsion) and saline infused during the procedure. Group 3 underwent similar torsion and retorsion but r-Hu EPO 5000 IU/KgBW was infused during the procedure. All the testes were harvested from rats 48 hours after surgery and evaluated histologically, assessing seminiferous tubule diameter, tubule semi- niferous density, loss of germ cell layers, and disarray of germ cell layers. Immuno- histochemistry examination to assess apo- ptotic mechanism. Result: There was a significant difference in the indicators of histological damage between groups 1 and groups 2 and 3. The damage was significantly less in group 3 than in group 2. Apoptosis is less detected in group 1 than in group 2 and group 3, and was significantly less in group 3 than in groups 2. Conclusion: These results suggest that erythropoietin has protective effect on seminiferous tubule damage after testicu- lar torsion, and preventing apoptosis pro- cess of germinal cells. MP-21.16 (Podium) Primary laparoscopic retroperitoneal lymph-node dissection for clinical stage I nonseminomatous germ-cell testis tumor: long term results Castillo O 1,2 , Campero JM 3 , Sanchez- Salas R 1 , Secin F 4 , Vitagliano G 1 , Diaz M 1 , Aranguibe JC 1 , Foneron A 1 1 Section of Endourology and Laparo- scopic Urology, Clı ´nica Santa Marı ´a, San- tiago, Chile; 2 Facultad de Medicina, Uni- versidad de Chile, Santiago, Chile; 3 Department of Urology. Clı ´nica Las Condes, Santiago, Chile; 4 CEMIC, Buenos Aires, Argentina Introduction: There is controversy re- garding the efficacy of the laparoscopic retroperitoneal lymph-node dissection (L- RPLND) as an alternative to the open ap- proach for the management of nonsemi- nomatous germ cell testicular tumors (NSGCT). Our objective was to assess ret- rospectively the cancer control and mor- bidity of primary L-RPLND in patients with clinical Stage I NSGCT. Methods: We reviewed 172 patients with clinical Stage I NSGCT undergoing pri- mary L-RPLND between 1993 and 2007. A modified template dissection was per- formed. Patients with retroperitoneal me- tastases were offered adjuvant chemother- apy. Clinical and pathologic data have been recorded. Kaplan Meier curves were generated estimating time to recurrence. Results: Eighty-two (48%) patients had any embryonal component in the primary tumor and 35 (20%) had lymphovascular invasion in the orchiectomy specimen. The median (IQR) age, operative time, length of hospital stay, blood loss and number of lymph nodes retrieved was 28 years (24,33), 135 mins. (120, 180), 48 hs. (24, 48), 50 cc. (20, 100) and 14 (10,18). Lymph nodes were negative in 132 (77%) patients. Followup was available in 80 of these 132 patients. Of these, 7 patients had recurrence, one of them 33 months after L-RPLND. Median follow-up for pts. without recurrence was 14 mo (IQR: 4,35). The cumulative 3-year recurrence free rate for this group was 82% (95%CI: 64, 91). Retroperitoneum was the site of 5 recurrences (1 associated with mediasti- num) and three in the lungs. 32 patients had lymph nodes with metastatic testicu- lar cancer. Follow-up was available in 15 of these 32 patients. Fourteen underwent adjuvant chemotherapy and 2 patients had recurrence at 3 and 64 months. Both re- curred in the retroperitoneum, with one also recurring in the port sites (3 month). 17 (10%) of 172 patients had peri/opera- tive complications including vascular and non vascualar injuries. 4 patients required conversion to open surgery. Two patients needed blood transfusion. Retrograde ejac- ulation was registered in 3 patients. No perioperative deaths occurred. Conclusions: Laparoscopic RPLND can only be performed by highly specialized surgeons. Its oncologic safety needs to be prospectively evaluated in randomized trials. MP-21.17 (Podium) Paratesticular masses: the Mayo Clinic experience Tsao AK, Karnes RJ, Sebo TJ, Nehra A Departments of Urology and Anatomic Pathology, Mayo Clinic, Rochester, MN Introduction & Objectives: The majority of masses found within the scrotal sac are usually within the testes and neoplastic. However, a subset of these tumors arise from paratesticular tissues and are extrat- esticular. Paratesticular tumors, although infrequent, are associated with a high inci- dence of malignancy. Methods: A retrospective analysis of clini- cal characteristics and surgical outcomes of 29 patients from 1954-2006 was per- formed. Data abstracted included age, di- agnosis, date of surgery, pathologic fea- tures, recurrence, and follow-up time. Results: Twenty nine men underwent radi- cal orchiectomy for a diagnosed paratesticu- lar mass. The mean age was 52 years (14-86 MODERATED POSTER SESSIONS UROLOGY 70 (Supplment 3A), September 2007 165