International Journal of Health Sciences & Research (www.ijhsr.org) 99 Vol.2; Issue: 2; May 2012 International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Case Report Eosinophilic Appendicitis Presented As Mucocele: A Rare Clinical Entity Sunil V Jagtap 1**@ , Dhiraj B Nikumbh 1* , Ashok Y Kshirsagar 2*** , Sujata R Kanetkar 1*** , Ashish Bohra 1# ** Associate Professor, * Assistant Professor, *** Professor, # Assistant Lecturer 1 Dept. of Pathology 2 Dept. of Surgery KIMS University, Karad, Maharastra @ Correspondence Email: drsvjagtap@gmail.com Received: 19/04//2012 Revised: 3/05/2012 Accepted: 8/05/2012 ABSTRACT Eosinophilic appendicitis (EA) is a rare disease of unknown etiology. Histological hallmark of this entity is eosinophilic infiltration of the muscularis propria with accompanying edema separating muscle fibers. Mucocele of the appendix is a rare condition that frequently mimics abdominal tumors. There is no specific imaging technology to correctly diagnose this condition preoperatively. So proper diagnosis of mucocele is only made during a laprotomy and histopathology. We herein present a case of eosinophilic appendicitis presented with mucocele, which is extremely rare finding. To the best of our knowledge, this is the first case in the literature of EA presented as mucocele. Key words: Eosinophilic appendicitis, mucocele, appendix. INTRODUCTION Eosinophilic appendicitis (EA) is a rare clinical entity. It is characterized by acute presentation and grossly inflamed appendix with absence of neutrophils in muscle layer. Histological hallmark of this entity is eosinophilic infiltration of the muscularis propria with accompanying edema separating muscle fibers. [1] The gastrointestinal symptoms are dependent upon the predominant layer involved. [2] Diagnosis of eosinophilic appendicitis requires high index of suspicion and exclusion with various disorders that are associated with peripheral and tissue eosinophilia. [2] Mucocele is a descriptive clinical term for an abnormal mucous accumulation distending the appendicular lumen. [3] Mucocele is not diagnosed on