The feasibility of using Tuba-tuba….1 The feasibility of using Tuba-tuba plant (Jatropha curcas L.) in making pesticides. Group 2 BSEd-3A Biological Science Abstract Jatropha curcas L. commonly known as Tuba-tuba is one of the poisonous plant species in the Philippines. It contains phytotoxins that are said to be dangerous when ingested. Thus, the researchers came up with this idea of using this toxic property of this plant in preparing pesticides against common domestic pests. Moreover, the prepare pesticides were compared to a commercial pesticide in terms of its effects in killing pests. In like manner, aside from investigating for its pesticide potential, the researchers also studied the phytochemical aspects of Jatropha curcas L., specifically the odor, color, viscosity, and its time of effect to take place. Three consecutive trials were conducted in selected setup such as death rate of domestic pests using the prepared pesticides. Through it all, among all the prepared pesticides, the researchers found out that Formulation C was the best formulation in killing the domestic pest. Nowadays, thousands of unprecedented demands, including problems in the environment are constantly persisting in the local areas of the country. To specify, food poisoning is likewise one of the issues that predominates these past few years. The plant species Jathropa curcas L., locally known as Tuba-tuba, Tubang-bakod (Tag.), Kasla (Bis.), and Tagumbau (Ilk.) and ecumenically called as fig nut, physic nut and pig nut is diversely distributed throughout the country and has been subjected in several food poisoning cases (Manila bulletin, 2006). Local media reported that eight children in General Santos City suffered in extreme stomach pain after eating Tuba-tuba (Jathropa curcas L.) last September 9, 2010 (http://gmanews.tv). The same scenario is observed in La Paz, Iloilo wherein fourteen school children experienced the same symptoms after eating Tuba-tuba fruit and were eventually rushed to a hospital (http://www.gmanews.tv). The prime reason why Tuba-tuba fruits and seeds result stomach pain and vomiting is because it contains poison which scientifically labeled as curcin. It is a phytotoxin (toxalbumin) which is large, complex protein molecule of toxicity. Additionally, curcin is said to be highly irritant. Consequently, Jatropha resembles other toxins such as hydrocyanic acid, dermatitis