1 United Memorial Hospital, Batavia, New York. 2 Department of Pharmacy Practice, Albany College of Pharmacy; and 3 The Endocrine Group, LLP, Albany, New York. These data were presented as a poster at the 2006 American Society of Health-System Pharmacists Mid-Year Clin- ical Meeting, December 6, 2006, Anaheim, CA. DIABETES TECHNOLOGY & THERAPEUTICS Volume 10, Number 2, 2008 © Mary Ann Liebert, Inc. DOI: 10.1089/dia.2007.0244 A Glucose Meter Accuracy and Precision Comparison: The FreeStyle Flash Versus the Accu-Chek Advantage, Accu-Chek Compact Plus, Ascensia Contour, and the BD Logic LINDA E. THOMAS, Pharm.D., 1 MICHAEL P. KANE, Pharm.D., F.C.C.P., B.C.P.S., 2 GARY BAKST, M.D., 3 ROBERT S. BUSCH, M.D., F.A.C.E., 3 ROBERT A. HAMILTON, Pharm.D., 2 and JILL M. ABELSETH, M.D., F.A.C.E. 3 ABSTRACT Background: This study compared the accuracy and precision of five blood glucose (BG) meters. Methods: Diabetes patients undergoing venipuncture for glucose testing were randomized to one of two groups consisting of three meters: FreeStyle ® Flash (Abbott Diabetes Care, Alameda, CA), Accu-Chek ® Advantage (Roche Diagnostics Corp., Indianapolis, IN), and Accu-Chek Com- pact Plus (Roche Diagnostics) or FreeStyle Flash, Ascensia ® Contour ® (Bayer Healthcare, Diag- nostic Division, Tarrytown, NY), and BD Logic ® (BD Diabetes Care, Franklin Lake, NJ). Within 5 min following venipuncture, duplicate finger BG measurements from three ipsilateral fingers were taken. Finger glucose measurements were compared with laboratory reference values. Ac- curacy was assessed by a Clarke error grid analysis (EGA) and within 10% of the laboratory value criteria. Meter precision was determined by calculating the absolute mean differences in glucose values between duplicate samples. Results: Finger sticks were obtained from 202 patients. Mean venipuncture BG was 148 mg/dL (SD  64 dL; range 25–439 dL). Accuracy by Clarke EGA (Zone A results) was demonstrated in 69% of Advantage samples, 75% of Compact Plus, and 96% of the first group of Flash versus 88% of the Contour, 67% of the Logic, and 91% of the second Flash samples (P  0.05 for both Flash and Contour). Meter accuracy using the 10% criteria was demonstrated in 30%, 38%, 70%, 46%, 48%, and 68% of the samples, respectively (P  0.05 for both Flash groups compared to each of the other meters). There were no differences in meter precision. Conclusions: No statistically significant differences in accuracy were evident using the Clarke EGA criteria (pooled results of Zone A and B), though the more strict 20% accuracy criteria (Zone A results only) found the Flash and Contour to have significantly greater accuracy compared to the Advantage, Compact Plus, and the Logic. Using the 10% accuracy criteria found the Flash to have significantly greater accuracy than each of the other four meters. All five meters dem- onstrated similar precision. 102