relation of clinical, radiologic, and histologic results as well as appro- priate follow-up is essential to detect the false-negative result earlier. 0539 Changes in Workflow Created by New Ultrasound Machines Michel Claudon, Service de Radiologie, France The global ultrasound market is roughly twice that of CT (in dollars). There are, in most countries, no restrictions on equipment purchase, and every physician may have access, with little need for sharing equipment. Portable units, which represented up to 25% of the market last year, are used increasingly outside the traditional hospital circuit, including emergency cases, with the expectation of better management of many patients in the most critical situations, as recently supported by emer- gency specialists. US is also widely recommended as a control method for IV line placement. 3D imaging is a well-assessed modality for fetal imaging for a few years, providing striking images of prenatal anomalies and being shown to improve both efficiency and confidence in diagnosis for fetal imag- ing. This new modality opens the door for a tremendous change in daily practice and workflow, associating a short acquisition time and a delayed post-treatment and reporting phase. Contrast-enhanced ultrasound is based on the intravenous administra- tion of microbubbles, which increase the backscattered signal, allowing real-time imaging of organs at very low output levels. Primary clinical application is focal liver lesions’ characterization and detection. This needs an adaptation of the workflow: e.g., placement of an IV line, assistance for injection, longer examination time, need for long clips storage and time for the physician for the post-treatment phase. Adaptation of the organization of the US section and optimization of the workflow is now an issue to get full benefit from new machines and modes. 0540 Sonographic Measurement of Liver, Spleen and Kidney Michael Kawooya, Makerere University/EC UREI Kampala, Uganda Background: Ultrasound scan is reliable for measurement of liver, spleen and kidney sizes. Normal measurements of these organs have been established in other populations but not in healthy African Ugan- dan children. Pathology of these organs commonly alters their sizes and ultrasound assessment is important in detecting pathological change in size. Objectives: To discuss the normal sonographic measurements for liver, spleen and kidneys in healthy children in Uganda, Africa and to compare these with measurements from other populations. To correlate the measurements obtained in Ugandan children with age, height and body weight and to compare this correlation with correla- tions from pediatric populations in other parts of the world. Methods: Data on sonographic measurements in Uganda was obtained through a cross-sectional study from June to November 2006 in five primary schools in Kampala district, Uganda. Heights and weights of 238 randomly selected healthy pupils aged 6-15 years were measured. Their liver, spleen and kidney sizes were then measured by ultrasound scan. The data was then computer processed. Literature was reviewed to compare findings from similar studies. Results: In Ugandan children, the lengths of the three organs showed the best correlation with age, height and body weight with weight showing the greatest correlation except for the spleen where height showed the greatest correlation. These observations are similar to studies from other populations. Conclusion: Normal sizes of the liver, spleen and kidneys in selected healthy Ugandan children have been documented. The lengths of these organs correlate with body weight, height or age, as is found in other pediatric populations. 0541 Ultrasound in the Digestive Tract Hassen Gharbi, IBN ZOHR, Tunisia US is today an important imaging modality for evaluation of the digestive tract in children. It allows simultaneous non invasive ana- tomic and homodynamic study. It’s of a diagnostic, prognosis, thera- peutic and preventive value. It helps the physicians to confirm eventual antenatal diagnosed abnor- malities and to treat children in several circumstances, exploring dif- ferent congenital and acquired disorders. US exam must be carried out by high frequency convex and linear probes in all scan plans. The child is lying in supine position, in general. No premedication is needed and diet is not necessary. Doppler techniques, if available, are helpful. Normal aspect of digestive tract and variants are important to be known. Its main indications are acute and chronic abdominal pain, suspected intussusception or appendicitis, inflammatory bowel diseases, sus- pected hypertrophic pyloric stenosis or gastro-oesophageal reflux, blunt abdominal trauma mid gut volvulus, Schoenlein Henock purpura syn- drome, mesenteric ischemia, and screening for abdominal congenital abnormalities. Checking all the intra abdominal organs must be the gold rule. The observation should include bowel wall thickness, bowel motility, bowel content, free fluid or collection in the abdomen, or any mass related to the bowel. US guided biopsy is very helpful, in particular when abdominal mass is suspected. US is needed during the follow up after medical or surgical treatment of several diseases: abscesses, ascitis, recurrencies of malignant tumors or intussusception. 0542 Use of Contrast Enhanced Ultrasonography (CEUS) in the Assessment of Focal Liver Lesions in Pediatric Patients Fulvia Terracciano, Endoscopy “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Italy Maria Pastore, Pediatry “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Italy Antonio Marseglia, Pediatry “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Italy Marco Sperandeo, Internal Medicine “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Italy Vito Annese, Endoscopy “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Italy Angelo Andriulli, Italy CEUS has improved diagnostic capacity of ultrasound (US) in the differential diagnosis of several pathologies in adults. At the present time, there are few controlled studies on the application of CEUS in focal liver diseases in children. AIM of this study was to assess the safety and the accuracy of CEUS in evaluating focal liver lesions in pediatric patients. Methods: 35 children (22 males, age range: 5-17 years) with focal liver lesions were investigated. All patients underwent also other concomi- tant diagnostic methods ( Magnetic resonance (MRI), computed to- mography (CT), biopsy or surgery). CEUS findings were compared with those obtained by CT and MRI. Results: The final diagnosis were: 2 HCC, 2 LNH, 6 metastasis; 13 angiomas, 4 focal steatosis, 3 liver abscess and 4 IFN. The CEUS S78 Ultrasound in Medicine and Biology Volume 35, Number 8S, 2009