154 Int. J. Telemedicine and Clinical Practices, Vol. 2, No. 2, 2017 Copyright © 2017 Inderscience Enterprises Ltd. Evaluating the role of perceived usefulness in user adoption of mobile immunisation notification system in Uganda Jackson Abandu* Department of Computer Science, Faculty of Science, Gulu University, Uganda Email: j.abandu@gu.ac.ug *Corresponding author Florence N. Kivunike Department of Information Technology, Faculty of Computing and Information Sciences, Makerere University, Uganda Email: fkivunike@cis.mak.ac.ug Abstract: The study sought to evaluate the role of perceived usefulness in user adoption of mobile immunisation-notification system in Uganda. Descriptive survey design was employed and structured questionnaires were administered to 51 healthcare professionals and mothers from Gulu referral and Gulu independent hospitals in Northern Uganda using purposive sampling technique. Regression analysis was performed to evaluate the impact of the identified antecedents on the intention to adopt IMUNOT through perceived usefulness based on technology acceptance model. The findings showed e-health knowledge, accessibility, support, content and trust as the antecedents of perceived usefulness with 87.8% of variance. The findings suggest the importance of perceived usefulness in the mobile Immunisation-notification system adoption. The study provides behavioural and infrastructural strategies for stakeholders on how to foster perceived usefulness in the system adoption. However, more variables may be evaluated to improve the analytical capability of the model. Keywords: perceived usefulness; immunisation; notification; adoption and mobile e-health; Uganda. Reference to this paper should be made as follows: Abandu, J. and Kivunike, F.N. (2017) ‘Evaluating the role of perceived usefulness in user adoption of mobile immunisation notification system in Uganda’, Int. J. Telemedicine and Clinical Practices, Vol. 2, No. 2, pp.154–167. Biographical notes: Jackson Abandu is an Assistant Lecturer in the Department of Computer Science, Faculty of Science Gulu University, Uganda. He received his Master’s in Information Technology from Makerere University. His research is concerned with the design and modelling of e-health and natural resource management systems for community or national development.