Ajitha M B et al / International Journal of Biomedical Research 2017; 8(03): 154-157. 154 IJBR (2017) 08 (03) www.ssjournals.com International Journal of Biomedical Research ISSN: 0976-9633 (Online); 2455-0566 (Print) Journal DOI: https://dx.doi.org/10.7439/ijbr CODEN: IJBRFA Original Research Article Comparative study of fine needle aspiration cytology, trucut biopsy and final histopathological examination in breast lumps Ajitha M B, Vinod Babu B * and Avinash Chandra Singh Department of General Surgery, Bangalore Medical College and Research Institute, Bangalore, Karnataka, India QR Code *Correspondence Info: Dr. Vinod Babu B, Post Graduate Student Department of General Surgery, Bangalore Medical College and Research Institute, Bangalore, Karnataka, India *Article History: Received: 03/01/2017 Revised: 14/01/2017 Accepted: 14/01/2017 DOI: https://dx.doi.org/10.7439/ijbr.v8i3.3829 Abstract Background: A lump in the breast results in anxiety for the patient and her family whether benign or malignant. Histological tissue diagnosis is a universally accepted means of definitive diagnosis of a breast lump. FNAC gives a rapid diagnosis and can be carried out in outpatient services with minimal trauma. Hence FNAC is gaining wide acceptance. Trucut biopsy is a safe method for a histological diagnosis, in operable breast cancer cases and a reliable technique to assess hormone receptor status. The trucut needle is a very handy instrument and it is now replacing the incision or excision biopsy. Aim: To find out the diagnostic accuracy of FNAC and trucut biopsy as compared to the final histopathological report in breast lumps. To compare diagnostic accuracy of FNAC and trucut biopsy in differentiating the benign and malignant lesions of palpable breast lumps. Methodology: This is a prospective study which included 70 patients having breast lump were subjected to FNAC and Trucut biopsy in Victoria hospital, Bangalore between October1, 2015 to September30, 2016 and were compared to final tissue diagnosis after subsequent admission and treatment. Various factors like age, size, duration, marital status, menstrual status and site were studied during statistical analysis. Results: There were 70 patients who presented with breast lump during the study period. Out of a total 70 breast lump study, final diagnosis was 36 benign breast lump and 34 malignant breast lumps. Sensitivity of FNAC and TRUCUT biopsy were 86.84% and 97.14% respectively. While TRUCUT was more accurate when compared to FNAC. Keywords: FNAC, Trucut biopsy, breast lump, breast malignancy. 1. Introduction Breast Lump is the commonest presenting symptom to breast clinic. The specificity and sensitivity of FNAC as diagnostic tool of breast cancer is actually controversial subject of discussion. Despite the wide spread use of FNAC for palpable breast lumps, it is not very helpful in preoperative decision making and management process by surgeon and oncologist.[1] In breast lump work up, triple assessment protocol is followed which includes clinical breast examination, radiological and pathological evaluation. Though FNAC technique is simple, patient don’t prefer repeated needling of their breast lump. [2] Also for fear of overtreatment, many surgeons are reluctant to accept cytology reports, often ambiguous and lacking in standardization of terminology as a basis for definitive surgery.[3] FNAC reports have percentage of uncertainty, also lack important information about the histopathological type, grade, receptor status and intrinsic behavior of the tumour. All these information are of great importance for correct pre-op evaluation.[4] Trucut biopsy is simple and safe technique. Patient’s acceptance is also high and positive diagnosis of malignancy by trucut biopsy, a definitive surgery can be planned.[5]