This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/bab.1426. This article is protected by copyright. All rights reserved. 1 Title SIMPLE PROCEDURE APPLYING LACTOSE INDUCTION AND ONE STEP PURIFICATION FOR HIGH YIELD PRODUCTION OF rh cIFN Authors Hamid Bashir 1 , Nadeem Ahmed 1* , Ahmad Usman Zafar 1 , Mohsin Ahmad Khan 1 , Saad Tahir 1 , Muhammad Islam Khan 1 , Faidad Khan 1 and Tayyab Husnain 1 1 National Centre of Excellence in Molecular Biology, 87-West canal Bank Road, University of the Punjab, Lahore-53700, Pakistan. *Corresponding Author Nadeem Ahmed National Centre of Excellence in Molecular Biology, 87-West Canal Bank Road, University of the Punjab, Lahore-53700, Pakistan Tel No:+9204235293141 Fax:+9204235293147 E-mail Address: nadeem.ahmed@cemb.edu.pk Running Title: One step chromatography for increased yield of consensus interferon