International Journal of Academic Scientific Research ISSN: 2272-6446 Volume 4, Issue 4 (November - December 2016), PP 117-123 www.ijasrjournal.org www.ijasrjournal.org 117 | Page Prevalence and Characteristics of Mitral Valve Prolapse in Adult Echocardiography Population in King Abdulaziz Medical City Over a 10Year Period Mohammad G. Al Ghamdi 1 , Yara O. Al Khodair 2 , AlAnoud K. Al Kahtani 2 1 Cardiology Consultant/King Abdulaziz Cardiac Center / King Abdulaziz Medical City -Riyadh, Saudi Arabia 2 Medical Intern/College of Medicine/ King Saud bin Abdulaziz for Health Sciences-Riyadh, Saudi Arabia Abstract Background: Mitral Valve Prolapse (MVP) is a well-recognized pathological entity that is associated with significant morbidity. Prevalence, pathological characteristics and clinical outcome of MVP in Saudi Arabia has not been estimated. Aims: Aim of the study is to estimate the prevalence, and type of management practices of MVP among an adult population who underwent echocardiographic (echo) evaluation at King Abdulaziz Cardiac Center (KACC) over 10-year period. Methods: Retrospective review of consecutive echo database (Xcelera®) studies performed for adult ( ≥ 14 y) patients at KACC between January 2002 and December 2011. Out of 53,258 database subjects, 232 definite myxomatous MVP cases were identified and included in the study. Mitral valve diseases other than myxomatous MVP were excluded. Results:Prevalence of MVP was 33 cases per 10,000 echo studies and average annual incidence was 3 cases per 1000 echo studies per year. Mean age at first echo evaluation was 40 ± 18 years. Saudi nationals represented 87% of cases, mostly of male gender (65%). Frequencies of bi-leaflet, posterior leaflet and anterior leaflet were 37.5%, 33.5% and 29% respectively. Hemodynamically significant MVP was present in 55% of cases with 30% of cases having flail segments and 18% having ruptured chordae. One third of patients (34%) underwent surgical intervention, mostly in form of valve repair (89%). Conclusion: MVP in this large echo-based population seems to be less prevalent than internationally known figures. Under-detection of MVP in the community might be a reason behind the low prevalence and late referral for a tertiary care management. Community-based physical screening and multicenter MVP registry are recommended. Keywords: Adult population, Echocardiogram, Kingdom of Saudi Arabia, Mitral Valve Prolapse, Mitral Valve Repair, Myxomatous Mitral Valve. INTRODUCTION Over the past 50 years, mitral valve prolapse (MVP) as a distinct clinical entity has undergone major evolution with respect to diagnosis and management approach 1 . Clinical manifestations and complications of MVP are discussed elsewhere, however it is the leading cause of nonischemic mitral