Downloaded from Medico Research Chronicles “Squamous papilloma of the retro commissure area: A case report and review of literature” Tiwari R., et al., Med. Res. Chron., 2017, 4 (4), 380-386 Medico Research Chronicles, 2017 380 Submitted on: June 2017 Accepted on: July 2017 For Correspondence Email ID: SQUAMOUS PAPILLOMA OF THE RETRO COMMISSURE AREA: A CASE REPORT AND REVIEW OF LITERATURE Ritu Tiwari 1 , Chaya M David 2 , Mahesh DR 3 , Alfred Joseph Ravikumar 4 , Priyank Sethi 5 , Rashmi KJ 6 1. MDS, Consultant Maxillofacial Radiologist, JSD Techno Dental Imaging Centre, Bangalore, Karnataka, India.. 2.MDS, Professor and HOD, Department of Oral Medicine and Maxillofacial Radiology, Dayananda Sagar College of Dental Sciences, Bangalore, Karnataka, India. 3. MDS, Reader, Department of Oral Medicine and Maxillofacial Radiology, Dayananda Sagar College of Dental Sciences, Bangalore, Karnataka, India. 4. MDS, Consultant Maxillofacial Surgeon, Thirty-two Dental Clinic, Chennai, Tamil Nadu, India. 5. MDS, PhD Scholar, Faculty of Dental Sciences, Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan, India. 6. MDS, Registrar, Oral Medicine & Maxillofacial Radiology. Kanva Sri Sai hospital. Case Study ISSN No. 2394-3971 Abstract Squamous papilloma is a HPV (Human Papilloma Virus) induced benign proliferation of stratified squamous epithelium. The lesion is of low virulence but of great clinical significance due to its variable clinical behavior. We present a report of squamous papilloma along with its review of literature which didn’t have the classic clinical appearance of papilloma but the histologic features were found to be consistent. Keywords: Cytopathic effect, Human Papillomavirus, Papilloma- squamous Introduction Oral papillary lesions are a heterogeneous group and present a range of clinical and histologic appearances. Squamous papilloma is one such benign epithelial tumor which can be seen in oral cavity and oropharynx. It is considered fourth most common oral mass and roughly accounts for 3-4 % of oral soft tissue lesions. 1 It presents as an exophytic growth (papillary or verrucous) with a pedunculated base and roughened, cauliflower like surface appearance. It results due to a benign proliferation of the stratified squamous epithelium and most common intra oral sites of occurrence are hard and soft palate, uvula, tonsil and epiglottis. 2 Histologically, they show a complex pattern of finger like projections with a central vascular zone, the papillary projections are covered by acanthotic stratified squamous epithelium depicting a normal pattern of maturation and occasionally basilar hyperplasia with plenty of koilocytes. 1,3 The lesions are usually associated with HPV 6 &11 but have a low infectivity rate and are not contagious. They are often asymptomatic and have a slow growth potential. Recurrence is rare after conservative excision. The lesion exhibits a spectrum of clinical appearance and there is a good chance of misdiagnosing it for something as sinister as carcinoma or other HPV associated lesions. Differential diagnosis includes verruca vulgaris, verruciform xanthoma, condyloma acuminatum and focal epithelial hyperplasia. 4,5 We present a case of