International Science and Investigation Journal ISSN: 2251-8576 2016, 5(4) Journal homepage: www.isijournal.info Continued Folic Acid Supplementation Throughout Pregnancy, May Cause Colorectal Cancer In The Future . Somayeh Zaminpira *1 , Sorush Niknamian 2 *1 Ph.D. in Cellular and Molecular Biology, University of Cambridge, United Kingdom 2 Ph.D. in Cellular and Molecular Biology, University of Cambridge, United Kingdom Abstract Folic acid supplementation during early pregnancy protects from spina bifida and avoids either a spontaneous miscarriage or a severe developmental defect causing early postnatal death, associated with spina bifida, microcephaly or anencephaly. However, Based on epidemiological data in both the U.S. and Canada showed an increase in the incidence of colorectal cancer beginning when folic acid fortification in wheat-based products became mandatory and continued folic acid supplementation throughout pregnancy can increase the risk of colorectal cancer in the future. Keywords: Pregnancy, Folic Acid Supplementation, Colorectal Cancer, Spina Bifida 1