ISSN (Print) : 2320 – 3765 ISSN (Online): 2278 – 8875 International Journal of Advanced Research in Electrical, Electronics and Instrumentation Engineering (An ISO 3297: 2007 Certified Organization) Website: www.ijareeie.com Vol. 6, I ssue 4, April 2017 Copyright to IJAREEIE DOI:10.15662/IJAREEIE.2017.0604014 2283 Texture Analysis of Thyroid Ultrasound Images for Diagnosis of Cancerous Nodule Using ART1 Neural Network Shrikant D. Kale 1 , Akash R. Dudhe 2 Assistant Professor, Department Electronics & Telecommunication Engineering, Jagadambha College of Engineering & Technology, Arni Road, Yavatmal, Maharashtra, India 1,2 ABSTRACT: A thyroid is largest endocrine gland, butterfly shape with two lobes which produces hormones that control metabolism body functions. The nodules are found in thyroid may be benign or malignant. The ultrasound (US) preferred over the other medical imaging modalities which is used to observe the subcutaneous body structures & internal organs for possible pathology or lesions. The physicians are deducing useful information concerning the tissue characterization and structure which is still subjective matter, Thus quantitative analysis of US images give the objective method for thyroid nodule diagnosis. In this paper, gray level co-occurrence matrix (GLCM) texture characterization techniques are used for feature extraction & extracted features are classified using adaptive resonance theory neural network (ART1) for diagnosis of thyroid nodule are described. The experimental results show the performance measure of classifier in terms of accuracy for the different vigilance parameter of ART1 neural network. KEYWORDS: Thyroid nodule, ultrasound (US), GLCM, ART1 Classifier. I.INTRODUCTION A thyroid is largest endocrine gland in the body, a butterfly shaped organ compose of the cone like lobes. It is located in the lower part of the neck below the Adam apple. The thyroid gland produces the T3 & T4 hormones that affects the heart rate, cholesterol level, body weight, energy level, mental state and controls a host of other body functions. Thus the function of thyroid is to regulate the body metabolism [1] . The thyroid diseases are common worldwide. In India too, there is significant burden of thyroid diseases. According to a projection from various studies on thyroid disease, it has been estimated that about 42 million people in India suffer from thyroid diseases. It covers the main five thyroid gland disease included the main five thyroid diseases: Hypothyroidism, Hyperthyroidism, Goiter, Autoimmune Thyroiditis, Thyroid cancer [2] . A National Cancer Registry program (NCRP) maintains the reliable data of cancer patient on the magnitude & pattern of cancer in India. The projection of thyroid cancer cases in year of 2010 is around 16,215 & by the year of 2020 goes up to 19,113. The cases of malignant thyroid nodule are found to be more in female to that of male. The projection of thyroid cancer in female for year of 2010, 2015 & 2020 is 11,751; 12,808 & 13,955 significant over male i.e. 4,464; 4,798 & 5,158 for the respective years. The other figures of thyroid disease are turn out to be significant in the Indian context. The preferred diagnosis method used for possible lesions are ultrasonography. [2] All radiological modalities like ultrasound, CT, Scintigraphy, SPECT, MR, PET, X-rays etc. play an important role in process of disease diagnosing and have become major evidence to ensure disease. But ultrasound (US) possesses a rare combination of advantages including portability, invasive, real-time data acquisition and affordability [3] . US are a diagnostic imaging tool used to visualize subcutaneous body structures and internal organs for possible pathology or lesions. The physicians are deducing useful information concerning the tissue characterization and structure. Thus, US have become an invaluable tool for the accurate diagnosis and follows up of different pathologies in a variety of tissues and organs [4] .