1 Splice Site Contribution in Alternative Splicing of PLP1 and DM20: Molecular Studies in Oligodendrocytes Grace M. Hobson, 1 Zhong Huang, 2 Karen Sperle, 1 Erik Sistermans, 3 Peter K. Rogan, 4 James Y. Garbern, 5 Edwin Kolodny, 6 Sakkubai Naidu, 7 and Franca Cambi 8 1 Nemours Biomedical Research, Alfred I. duPont Hospital for Children, Nemours Children’s Clinic, Wilmington, DE; 2 Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University; Philadelphia, PA, 3 Department of Human Genetics, University Medical Center, Nijmegen, The Netherlands; 4 Laboratory of Human Molecular Genetics, Children’s Mercy Hospital and Clinics, Kansas City, MO; 5 Department of Neurology and Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI; 6 Department of Neurology, New York University Medical Center, New York, NY; 7 Neurogenetics Unit, Johns Hopkins University School of Medicine, Kennedy Krieger Institute, Baltimore, MD 8 Departments of Neurology and Neurobiology, University of Kentucky, Lexington, KY Corresponding author: Grace M. Hobson, PhD Nemours Biomedical Research Alfred I. duPont Hospital for Children PO Box 269 Wilmington, DE 19899 Phone: (302) 651-6829 Fax: (302) 651-6899 Email: ghobson@nemours.org