58 International Journal of Contemporary Medical Research International Journal of Contemporary Medicine Surgery and Radiology Volume 2 | Issue 2 | April-June 2017 Evaluaion of the Outcome of Acute Pancreaiis by Ranson’s Criteria and Modiied CT Severity Index Prem Chand 1 , Rommel Singh 2 , DP Singh 3 , Nisha Rani 4 1 Associate Professor, 2 Assistant Professor, 3 Professor, 4 Junior Resident, Department of Surgery, GMC, Paiala, India Corresponding author: Dr Rommel Singh, Assistant Professor, Department of Surgery, GMC, Paiala, India How to cite this aricle: Prem Chand, Rommel Singh, DP Singh, Nisha Rani. Evaluaion of the outcome of acute pancreaiis by Ranson’s criteria and modiied CT severity index. Internaional Journal of Contemporary Medicine Surgery and Radiology. 2017;2 (2):58-61. INTRODUCTION Acute pancreatitis is a reversible pancreatic parenchymal injury associated with inlammation. 1 Severe acute pancreatitis develops in about 25% of patients with acute pancreatitis. Acute pancreatitis has widely variable clinical and systemic manifestations spanning the spectrum from a mild, self-limiting episode of epigastric pain to severe, life-threatening, multiorgan failure including sepsis, renal failure, acute respiratory distress syndrome and death. he 1992 Atlanta classiication deined severe acute pancreatitis as the presence of organ failure or local complications such as pancreatic necrosis. Revised Atlanta classiication deined interstitial and necrotizing pancreatitis based on CT scan also included peripancreatic necrosis. 2 Severity is linked to the presence of systemic organ dysfunction and pancreatic necrosis. Morbidity of severe acute pancreatitis is biphasic. In the irst week it is strongly related to systemic inlammatory response while sepsis due to infected pancreatic necrosis leading to multiorgan failure syndrome occurs in the later course after the irst week. 3 Because of the variability and seeming unpredictability of acute pancreatitis, clinical scoring systems have been developed to predict the severity of acute pancreatitis and, as important, for patient stratiication and enrollment in clinical trials. 4 he present study was conducted to evaluate the outcome of acute pancreatitis by ranson’s criteria and modiied ct severity index. MATERIAL AND METHODS he study enrolled 30 patients with clinical diagnosis of acute pancreatitis presenting in the department of surgery, Rajindra Hospital, Govt. Medical College, Patiala. Routine labarotory investigations in all subjects including hemogram, liver function test, renal function test, serum calcium levels, serum amylase, serum electrolytes, ABG, ultrasonography abdomen, chest x ray, contrast enhanced CT of whole abdomen were done. CECT abdomen was done to diagnose, to access complications and severity of pancreatitis. Ranson's criteria is based on 11 clinical and laboratory parameters measured within the irst 48 hours of O riginal a rticle ABSTRACT Introducion: Acute pancreaiis is a reversible pancreaic parenchymal injury associated with inlammaion. Severe acute pancreaiis develops in about 25% of paients with acute pancreaiis. The present study was conducted to evaluate the outcome of acute pancreaiis by ranson’s criteria and modiied ct severity index. Material and methods: The study enrolled 30 paients with clinical diagnosis of acute pancreaiis presening in the department of surgery, Rajindra Hospital, Govt. Medical College, Paiala. Rouine labarotory invesigaions in all subjects including hemogram, liver funcion test, renal funcion test, serum calcium levels, serum amylase, serum electrolytes, ABG, ultrasonography abdomen, chest x ray, contrast enhanced CT of whole abdomen were done. All the data was recorded in a tabulated form and analysed using SPSS sotware. Chi square test was applied as a test of signiicance and p value of less than 0.05 was considered signiicant. Results: In our study Ascites was the most common complicaion with 16 (34.4 %) paients, Pleural Efusion second most common with 9 (19.14%), 5 (10.6%) paients developed Pseudocyst, 4 (8.51%) paients infected pancreaic necrosis, 3 (6.38 %) paients each Paralyic ileus and ARDS, 2 (4.25 %) paients each developed Walled of necrosis, Renal failure, Muli organ failure and one (2.12%) paient developed Pancreaic istula. Though most of the local complicaions were seen in paients with higher Ranson’s score but the values were staisically non-signiicant. Conclusion: We can conclude that both Ranson score and MCTSI plays a vital role in predicing paient’s outcome of acute pancreaiis. There was staically insigniicant diference amongst the systemic complicaions when Ranson score and MCTSI were compared but the local complicaions showed staically signiicant diference with MCTSI score. Keywords: Hemogram, Pancreaiis, Ranson, Ultrasonography