European Scientific Journal January 2018 edition Vol.14, No.3 ISSN: 1857 – 7881 (Print) e - ISSN 1857- 7431 140 Chromatographie Sur Couche Mince Et Activité Antiradicalaire D’extraits De Pupalia Lappacea (L.) Juss. Amaranthaceae Mamadou Aïssa Jazy Laboratoire de Botanique- Pharmacognosie, Faculté des Sciences de la Santé, Université Abdou Moumouni, Niamey-Niger Mahamane Haïdara, Rokia Sanogo DER des Sciences Pharmaceutiques, Faculté de Pharmacie, Université des Sciences, Techniques et Technologies de Bamako-Mali. Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, Ministère de la Santé Publique, Bamako-Mali Doi: 10.19044/esj.2018.v14n3p140 URL:http://dx.doi.org/10.19044/esj.2018.v14n3p140 Abstract Introduction: P. lappacea is a plant used in traditional medicine, in the regions of Niamey and Tillaberi, as anti-hemorrhoids. It contains tannins, sterols, triterpenes, saponosides, mucilages, anthracene derivatives, oses and holosides for which it is necessary to appreciate the activities relating to the medicinal virtues. Objective: To contribute to the phytochemical and pharmacological study of Pupalia lappacea, through the semi-quantitative estimation of phytocomposés and the research of the antiradical power of its various extracts. Methodology: Phytochemical screening, semiquantitative estimation and a study of the antioxidant activity of phytocomposites were carried out by thin layer chromatography (TLC) from extracts obtained with increasing polarity solvents. Results: All P. lappacea extracts contain a large number of bioactive chemical compounds. Substances with anti- haemorrhoidal activity (phenolic compounds, tannins) are found mainly in the aqueous extracts (digested, decoct exhausted) and the methanolic extract. The strongest antiradical activity observed with the digest and the spent decoction after migration in the solvent system. Ethyl acetate - Methyl ethyl ketone - Formic acid - Water (5-3-1-1) would be linked to phenolic compounds. A less severe free radical activity, probably due to terpenic substances, was observed with the BAW solvent system (60-15-25). The extract corresponding to the traditional (decocted) use of P. lappacea also has low antioxidant activity. Conclusion: The use of P. lappacea as anti- hemorrhoid is justified. However, the digest and the spent decoction would have greater anti-hemorrhoidal properties than those of the decoction obtained