In multiple linear regression analysis we found signifi- cant correlation between 6MWD and BMI (b = 0.41, p < 0.0001) and arterial hypertension (b = À0.16, p = 0.04). Females had significantly shorter 6MWD than males (401.1 ± 83.6 m and 451.8 ± 107 m, respec- tively; p = 0.01). Difference was significant after adjust- ment for BMI and age (analysis of covariance) – R = 0.61, R 2 = 0.38 (p < 0.0001). Conclusions: BMI, female sex, arterial hypertension and lower: daytime PaO 2 , FVC, FEV 1 were related to short- er 6-min walking distance in OSA patients. doi:10.1016/j.sleep.2006.07.266 P458 Even non-apneic snoring women from the general population show symptoms of sleep-disordered breathing M. Svensson 1,* , C. Janson 2 , K. Franklin 4 , J.-E. Broman 3 , J. Theorell-Haglo ¨w 2 , E. Lindberg 2 1 Department of Surgical Sciences, Otolaryngology and Head- and Neck Surgery 2 Department of Medical Sciences, Respiratory Medicine and Allergology 3 Department of Neuroscience, Psychiatry, Uppsala Uni- versity, Uppsala, Sweden 4 Department of Respiratory Medicine, University Hos- pital, Umea ˚ , Sweden Objectives: Snoring is often regarded as harmless when not associated with apneas, and not considered to need treatment. The aim of this study was to investigate symptoms associated with snoring and compare them to symptoms of OSA in a population-based sample of women. Materials and methods: A population-based sample of 400 women aged 20 – 70 years underwent a full-night polysomnography and answered questionnaires con- cerning potential symptoms of sleep-disordered breath- ing. Non-snoring subjects with an apnea-hypopnea index (AHI) < 15 served as controls (n = 183). Group 1 comprised subjects with habitual snoring but without sleep apnea (AHI < 15, n = 78), group 2 non-snoring subjects with AHI P 15 (n = 60), and group 3 habitual snorers with AHI P 15 (n = 74). Results: Compared to controls, all three groups reported significantly higher prevalences of dry mouth on awak- ening (16% in controls, compared to 35, 33 and 50%, respectively). Nocturia was associated with AHI of P15 (controls = 34%, group 2 = 52% (p = 0.02); group 3 = 56% (p = 0.001)) but not to snoring without sleep apnea. Several symptoms were reported more often among snorers regardless of the presence of apneas; waking up unrefreshed in the morning (controls = 20%, group 1 = 41% (p = 0.0006); group 3 = 37% (p = 0.005)); falling asleep involuntarily during day (controls = 6%; group 1 = 20% (p = 0.001); group 3 = 16% (p = 0.009)) morning headaches (con- trols = 27%; group 1 = 40% (p = 0.04); group 3 = 42% (p = 0.02)); and excessive daytime sleepiness (con- trols = 15%; group 1 = 32% (p = 0.002); group 3 = 27% (p = 0.04)). For the non-snoring women with sleep apnea the prevalence of these symptoms did not significantly differ from controls. Conclusion: In a population-based sample of women snoring is associated with several symptoms regardless of concomitant sleep apnea. If the aim of treatment is to reduce symptoms, these data indicate that also habit- ual snorers without sleep apnea should be offered treatment. doi:10.1016/j.sleep.2006.07.267 P459 Profile of elderly persons with sleep disordered breathing with and without insomnia Peter Johansson 1,2,* , Urban Alehagen 1,2 , Ulf Dahlstrom 1,2 , Eva Svanborg 3,4 , Anders Brostrom 1,2,3 1 Department of Cardiology, Linkoping University Hos- pital, S-58185 Linkoping, Sweden 2 Department of Medicine and Care, Faculty of Health Sciences Linkoping University, Linkoping, Sweden 3 Division of Clinical Neurophysiology, Linkoping Uni- versity Hospital, S-58185 Linkoping, Sweden 4 Department of Neuroscience and Locomotion, Faculty of Health Sciences Linkoping University, Linkoping, Sweden Background: Sleep disordered breathing (SDB) and insomnia are common sleep disturbances, especially among elderly persons. Their co-existence is however complex. In patients with SDB there are often discrep- ancies between objective measures of sleep and self-re- ports of sleep quality. Aim: To investigate if there are any differences in param- eters of SDB, psychiatric disturbances, as well as day- time sleepiness in those having SDB with and without insomnia. Design and methods: A cross sectional cohort design was used. 346 elderly subjects (47% males), 75–85 years vol- unteered for a one night home sleep respiratory record- ing. The participants also answered to questionnaires regarding sleeping problems (Uppsala Sleep Inventory Questionnaire), psychiatric disturbances (Hospital Anx- iety Depression Scale) and EDS (Epworth Sleepiness Scale). Results: SDB (AHI > 5) occurred in 56% (n = 189) of the subjects (55% males, p < 0.05). Concerning parame- ters of SDB no significant differences between complain- ers and non-complainers of insomnia were found. But Abstracts / Sleep Medicine 7 (2006) S1–S127 S115