IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 17, Issue 7 Ver. 2 (July. 2018), PP 53-57 www.iosrjournals.org DOI: 10.9790/0853-1707025357 www.iosrjournals.org 53 | Page Intolerance to Total Dentures by the Patients Jadranka Bundevska 1 , Biljana Kapusevska 1 , Natasha Stavreva* 1 , Vesna Jurukovska Shotarovska 1 , Budima Pejkovska Shahpaska 1 1 (Department of Prosthodontics, Faculty of Dentistry, University “St. Cyril and Methodius” Skopje, Macedonia) *Corresponding author: Jadranka Bundevska Abstract: Introduction. In everyday dental practice, when making total dentures a common problem is intolerance of the patients. Purpose. To alleviate the inconvenience and allow patients to quickly and easily accept the new dentures. Material and methods. In this study we divided the patients who manifested intolerance to total dentures into three groups of ten patients. After handing over the dentures and examining the nature of intolerance, the first group included patients with the crucial role of dentures taking the factor of time, as a period of adaptation to something new and foreign. In the second group we included patients who during the process of making total dentures had the problem of nausea and vomiting. The third group consisted of patients in whom we cut the finished dentures pharyngeal and lingual, at their request, and yet in accordance with the basic prosthetic principles. Results. After a certain period we achieved success in the three groups, but the biggest and the fastest success we achieved with the second group, where after only 10 days taking medications (Reglan, Dramina) patients accepted total dentures and success was evident. Conclusion. In case of manifested intolerance to total dentures, an individual approach to solving the problem is required. Therefore, always approach the therapy that you think that in a particular patient you will achieve a faster and greater loss of the factor of intolerance to total dentures. Keywords – intolerance, total dentures, edentulism, adaptation --------------------------------------------------------------------------------------------------------------------------------------- Date of Submission: 24-06-2018 Date Of Acceptance: 09-07-2018 --------------------------------------------------------------------------------------------------------------------------------------- I. Introduction Tooth loss is a major problem worldwide, one with adverse oral, systemic, and mental health effects. Edentulous participants experience such difficulties as problems with chewing food, weakened facial musculature, degradation of the supporting alveolar structures, reduced bite-force and chewing efficiency, gastrointestinal disorders, and difficulties with socializing or forming close relationships. Rehabilitation with dentures can alleviate these adverse effects to some degree and provide a sense of normalcy, allowing the patient to interact with others. [1-4] Removable dentures have been used as one method to compensate for missing teeth for a long time. [5] The success of dentures is related to many factors. These include technical procedures, functional factors, esthetics, biologic determinants and psychological factors. Psychological factors include the preparedness of the patients and their mental attitudes towards dentures, their relationship with and attitude toward the dentist, their intelligence and ability to learn how to use the dentures and their personalities. [6] The teeth are there to replace what you have lost and the denture base holds it all in place while covering the palatal, or the roof of the mouth. Unfortunately, this can cause the issue of intolerance to the dentures, nausea and even vomiting. Not all people can tolerate having their palatal area covered. The palatal area is gag zone, this triggers the Vagus nerve in the brain to activate and cause the person to gag. Statistics show that 57% of Americans aged 65 to 74 wear some form of dentures. 51% of Americans aged 55 to 64 have either full or partial dentures. That is a huge part of the population trying to avoid denture intolerance and denture problems. [7] There is a different approach to managing the severe denture intolerance (gag reflex) problem in the dental literature: 1. Clinical techniques 2. Prosthodontic management 3. Pharmacologic measures 4. Psychologic intervention