28 Toxicol. Environ. Health. Sci. Vol. 8(1), 28-42, 2016
The concentrations of the US EPA 16 priority polycy-
clic aromatic hydrocarbons (PAHs) were measured
in honey samples collected from different regions of
Nigeria with a view to providing information on the
extent of contamination, regional profiles, sources
and risks of PAHs in this food type. The concentra-
tions of the PAHs were determined by using gas
chromatography-mass spectrometry after extraction
by ultra-sonication with n-hexane and dichlorometh-
ane. The concentrations of 16 PAHs in the honey
samples ranged from 169-522 μg kg
-1
, 97.2-1980 μg
kg
-1
, 180-641 μg kg
-1
and 122-357 μg kg
-1
for South-
East, South-West, Niger Delta, and North Central
regions respectively. The compositional patterns of
PAHs in the analyzed honey samples followed the
order: 5-rings >4-rings >3-rings >6-rings >2-rings.
The estimated daily intake values from consumption
of these honey samples ranged from not detected
(nd) to 1.9 ng kg
-1
bw day
-1
, nd to 5.9 ng kg
-1
bw day
-1
,
nd to 18 ng kg
-1
bw day
-1
and 0.6 to 33 ng kg
-1
bw
day
-1
for BaP, PAH2, PAH4 and PAH8 respectively.
The incremental life cancer risk and margin of expo-
sure values for the majority of the samples indicate
that there is no risk associated with the consump-
tion of these honey samples. The PAH isomeric
ratios and principal component analysis indicated
that combustion of fossil fuels, natural gas and bio-
mass, and automobile emissions were the main
sources of PAHs in these samples from the different
regions of Nigeria.
Keywords: Honey, Polycyclic aromatic hydrocarbons, Risk
assessment, Nigeria
Introduction
Honey is a natural product produced by Apis mellifera
bees from the nectar or secretions of plants, and does
not usually contain any additives or preservatives
1
. It
contains a number of nutritionally valuable compounds
and has healing, prophylactic, anti-oxidative, anti-bac-
terial and immune-enhancing properties
2,3
. Honey is
made up of a mixture of carbohydrates, such as fruc-
tose (25-45% m/m), glucose (25-37% m/m), maltose
(2-12% m/m) and sucrose (0.5-3% m/m) with traces of
other sugars, and water (14-18% m/m)
4
as well as small
amounts of a wide array of vitamins, mineral substances
(0.1 to 1.0% m/m)
5
, amino acids and antioxidants
1
. The
colour, flavour, carbohydrate composition and mineral,
amino acid and antioxidant content of honey often var-
ies with floral types
1
. The concentrations of contami-
nants in honey reflect the conditions of the environ-
ment and bee-keeping practices. Since the forage area
of the bee hive is very large (more than 7 km
2
) and the
bees come in contact with the basic components of the
environment (air, soil and water), the concentrations of
contaminants in honey reflect their amounts in the
whole region
4
. Thus, honey can serve as a useful envi-
ronmental marker and bioindicator for monitoring en-
vironmental contaminants
6-9
. Despite the known nutri-
tional and therapeutic properties of honey, the occur-
rence of xenobiotics, such as metals, pesticides and
polycyclic aromatic hydrocarbons, in honey may con-
stitute a serious threat to consumers.
Polycyclic aromatic hydrocarbons (PAHs) are a di-
verse group of over one hundred (100) organic com-
pounds consisting of two or more fused aromatic rings
10
and/or pentacyclic rings in linear, angular or cluster
formations
11-13
. PAHs are primarily produced by the
Chukwujindu M. A. Iwegbue
1
, Godswill O. Tesi
1
,
Grace Obi
2
, Grace E. Obi-Iyeke
3
,
Ufuoma A. Igbuku
1
& Bice S. Martincigh
4
1
Department of Chemistry, Delta State University P.M.B. 1, Abraka,
Nigeria
2
Department of Chemistry, Federal University of Petroleum
Resources, Effurun, Delta State, Nigeria
3
Department of Botany, Delta State University P.M.B. 1, Abraka,
Nigeria
4
School of Chemistry and Physics, University of KwaZulu-Natal,
Westville Campus, Private Bag X54001, Durban, 4000, South
Africa
Correspondence and requests for materials should be addressed
to C. M. A. Iwegbue (maxipriestley@yahoo.com)
Received 9 July 2015 / Received in revised form 27 December 2015
Accepted 8 January 2016
DOI 10.1007/s13530-016-0259-z
©The Korean Society of Environmental Risk Assessment and
Health Science and Springer 2016
pISSN : 2005-9752 / eISSN : 2233-7784
Abstract
Concentrations, Health Risks and Sources of Polycyclic
Aromatic Hydrocarbons in Nigerian Honey