IJSRSET1841205 | Received : 25 January 2018 | Accepted : 08 February 2018 | January-February-2018 [(4) 1 : 755-762 ]
© 2018 IJSRSET | Volume 4 | Issue 1 | Print ISSN: 2395-1990 | Online ISSN : 2394-4099
Themed Section : Science
755
Spectroscopic and Biological Studies of 3,5-
Dichlorosalicylaldehyde-3-Aminopyridine Schiff Base and
their Tellurium(IV) Complexes
Gobind Goyat, Anju Malik, Vikas, K. K. Verma, Sapana Garg
Department of Chemistry, Maharshi Dayanand University, Rohtak, Haryana, India
ABSTRACT
3,5-Dichlorosalicylaldehyde react with 3-aminopyridine to gives monobasic ON bidentate Schiff base ligand (3-
APY-{3,5-ClSalH}). TeCl4, ArTeCl3 and Ar2TeCl2: where Ar = 4-methoxyphenyl, 4-hydroxyphenyl, 3-methyl-4-
hydroxyphenyl, react with above Schiff base leads to seven new complexes: having formula [TeCl3(3-APY-{3,5-
ClSal})], [ArTeCl2(3-APY-{3,5-ClSal})] and [Ar2TeCl(3-APY-{3,5-ClSal})]. The purity of these compounds was
estimated by TLC technique, while their structures were supported by elemental analyses, conductance
measurement and spectroscopic methods such as
1
HNMR, infrared spectra giving pentacoordinated tellurium
centre having Ψ – trigonal bipyramidal geometry. Also, Schiff base ligand and some of their tellurium(IV)
complexes display biological activities in vitro against bacteria and fungii.
Keywords: 3,5-Dichlorosalicylaldehyde, Bidentate Schiff base, Tellurium(IV) Complexes.
I. INTRODUCTION
Schiff bases are considered as “privileged ligands”
because they are easily prepared by the condensation
product of carbonyl groups with amine[1-6]. Some
Schiff bases containing nitrogen and other donor
atoms are reported to possess antibacterial[1,7-12],
antifungal[9-13] and antitumor activities[14,15]. It is
reported[1,16] Schiff base containing
heteroatom[17,18] and a number of metal complexes
of Schiff bases derived from 2-aminopyridine and 2,3-
diaminopyridine with o-hydroxybenzaldehyde, p-
hydroxybenzaldehyde and p-nitrobenzaldehyde etc.
have been reported to possess antimicrobial
activity[19-30].
TeCl4 is also known to form adducts with amides[31-
38] and thiourea[39], thus reflecting its acceptor
behaviour. Also, aryltellurium(IV) chlorides are
known[31-36,40-57] to behave as lewis acids and
form complexes with several Nitrogen, Oxygen and
Sulphur donor bases. In view of this, we have
investigated the reactions of tellurium(IV) chloride
and aryltellurium(IV) chlorides with 3,5-
dichlorosalicylaldehyde-3-aminopyridine Schiff base
(3-APY-{3,5-ClSalH}), to synthesize some new
complexes of tellurium(IV).
II. METHODS AND MATERIAL
All chemicals used were of Analytical Reagent grade.
All preparations were carried out under an
atmosphere of dry N2 atmosphere. The solvents were
purified by standard method[58,59] before use. The
purity of compounds was checked by TLC using Silica
gel-G (Merck). Melting points were determined in
open capillary tube and are uncorrected.
Carbon, hydrogen and nitrogen analyses were
obtained microanalytically from SAIF, Panjab