108 JSIMLA Vol 10, No 2, September 2018 2018 South India Medico-Legal Association. All rights reserved. ORIGINAL COMMUNICATION SEXUAL FUNCTION OF DEPOT MEDROXYPROGESTERONE ACETATE USERS 1 Moudy E.U. Djami, 1 Indrayani, 1 Yanasita Mafluha, 2 Ong Tjandra, 2 Prilly Astari, 2 Erna J. Simatupang 1 Akademi Kebidanan Bina Husada, Tangerang, Indonesia 2 Sekolah Tinggi Kesehatan Bina Permata Medika, Tangerang, Indonesia Date of acceptance: 12/12/2017 ABSTRACT Background. Sexual satisfaction plays an important role in increasing woman health and quality of life. Sexual disfunction causes disharmony between couples resulting in doubts, loss of sexual desire and persistence of relationship. Hormonal contraceptive factors affect sexual disfunction. This study aims to determine the sexual function of depot medroxyprogesteron acetat (DMPA) and non-hormonal contraceptive users. Method. It is an analytical study using historical cohort design. Samples were divided into two groups, DMPA and non-hormonal contraceptive users using 47 respondents in each group. Data collecting was done from January to June 2016 in the area of Jalan Emas Primary Health Care. Samples were obtained using systematic random sampling technique. The instrument used was Female Sexual Function Index (FSFI). Statistical data was obtained using Mann Whitney and unpaired t-test. Results. Results of Mann Whitney statistical test showed no sexual function difference between DMPA and non-hormonal contraceptive users (p=0.883), but orgasm and pain during sexual intercourse scored higher in non-hormonal contraceptive compared to DMPA acceptors (12;6-14 vs 11;7-14), (9;5-4 vs 8;4-13). On the contrary, DMPA acceptors scored higher in arousal dimension (12;9-16 vs 6;2-8) and lubrication dimension (16;10-20 vs 12;8-16). Result of unpair t test showed a significant difference between sexual function of respondent age factor (score p=0.029) and couple age (score p=0.015). Conclusion. DMPA did not affect user’s sexual function. Other affecting factors were respondents and husbands’ age. Further studies were expected to examine other factors affecting the sexual func tion of DMPA injection contraceptive acceptors. Keywords: Sexual function, injection contraception, depot medroxyprogesteron acetate INTRODUCTION Sexual satisfaction plays an important role in increasing woman health and quality of life. 1 Sexual desires can be affected by biological, psychological and cultural factors. 2 Sexual disfunction does not only disrupt individual ability and creativity, but also causes disharmony between couples which may result in doubts and loss of desires as well as persistence of relationship. 3 Sexual disfunction may affect the ability to build and maintain intimate relationship, and it interacts with mental health conditions such as anxiety and depression. 4 It is in accordance with results of studies showing that 88% of listed divorce is caused by sexual problems. 5 Sexual disfunction can be affected by hormonal contraceptive factors. 6 Given the long- Corresponding author: Indrayani Email: indrayani_akbid@yahoo.co.id term impact of contraceptives, the fulfillment of ethical aspects must be ensured for every option taken. Injection of depot medroxyprogesteron acetate (DMPA) is a kind of hormonal contraceptions most frequently used by women. This contraception does not contain estrogen so that it is considered less influential to the globulin binding the sexual hormon 7 and free testosterone 8 which can turn down the sexual desires. Result of survey by Matson et.al showed that 15% DMPA users were identified to experience declining libido. 9 Declined or disrupted sexual function is a problem for contraceptive acceptors because it will affect the integrity of the family, which in turn lead to family disharmony, divorce, and children separation from intact families leading them to unhealthy lifestyles, such as illegal drug use, premarital sex, and other negative behaviors. This