Journal of Cancer Therapy, 2018, 9, 568-575 http://www.scirp.org/journal/jct ISSN Online: 2151-1942 ISSN Print: 2151-1934 DOI: 10.4236/jct.2018.97048 Jul. 23, 2018 568 Journal of Cancer Therapy The Impact of Obesity on Performing Lymphadenectomy and Its Outcome in Ovarian Cancer Patients Basel Refky 1 , Mosab Shetiwy 1 , Ahmed Zaki 2 , Mohamed Elmetwally 1 , Hanan Nabil 2 , Islam Abdou 1 , Ahmed Abdallah 1 , Amr Soliman 3 , Khaled Abdelwahab 1 , Anas Gamal 2 , Essam Elshiekh 4 , Khaled Gaballa 1* 1 Oncology Center Mansoura University, Mansoura, Egypt 2 Mansoura University Hospitals, Mansoura, Egypt 3 Oldenburg University, Oldenburg, Germany 4 Tanta Center, Tanta, Egypt Abstract Background: This study discusses the effect of obesity on the number of lymph nodes harvested during systematic LND and the LND-related compli- cations in ovarian cancer patients. Methods: This retrospective study enrolled women with ovarian cancer who were consecutively subjected to open surgic- al resection that included systematic LND (pelvic and para-aortic) in the On- cology Center in Mansoura University (OCMU) during the period between January 2012 and June 2017. Patients were categorized according to the rec- ommendations of World Health Organization by their BMI as non-obese (BMI < 30.0 kg/m 2 ) and obese (BMI ≥ 30.0 kg/m 2 ). Results: Seventy-seven women with ovarian cancer were enrolled in the study according to our inclu- sion and exclusion criteria. 43 females (55.8%) were grouped as obese and 34 (44.2%) as non-obese. Lymph nodes retrieved in total and in different stations separately (pelvic and para-aortic) were all similar among patients in both groups. LND-related intraoperative complications were observed in 8 patients (18.6%) in the obese group and 3 patients in the non-obese group (8.8%) (P = 0.347). Hospital stay was the same in the two groups with a median of 4 days (IQR 3 - 5). Postoperative complications occurred in 13 patients (30.2%) in the obese group and only in one patient (3%) in the non-obese group (P = 0.004). Conclusion: Obese ovarian cancer patients may safely undergo com- prehensive staging involving extensive lymph node dissection in open surge- ries without significant increase in the rates of intraoperative complications. How to cite this paper: Refky, B., Shetiwy, M., Zaki, A., Elmetwally, M., Nabil, H., Abdou, I., Abdallah, A., Soliman, A., Ab- delwahab, K., Gamal, A., Elshiekh, E. and Gaballa, K. (2018) The Impact of Obesity on Performing Lymphadenectomy and Its Outcome in Ovarian Cancer Patients. Journal of Cancer Therapy, 9, 568-575. https://doi.org/10.4236/jct.2018.97048 Received: June 25, 2108 Accepted: July 20, 2018 Published: July 23, 2018 Copyright © 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access