Barbach Y, Baybay H, Chaouche M, Dah Cherif A, Elloudi S, Mernissi FZ. Isolated Genital Psoriasis - Rare and Disabling Location. Int J Clin Dermatol Res. 2018;6(7):185-187. 185 OPEN ACCESS https://scidoc.org/IJCDR.php International Journal of Clinical Dermatology & Research (IJCDR) ISSN 2332-2977 Isolated Genital Psoriasis - Rare and Disabling Location Case Report Barbach Y * , Baybay H, Chaouche M, Dah Cherif A, Elloudi S, Mernissi FZ Dermatology Department, University Hospital Hassan II, Morocco. *Corresponding Author: Younes Barbach, Dermatology Department, University Hospital Hassan II, Morocco. Tel: +212671797158 Fax: 0535613729 E-mail: dr.younes2011@gmail.com Received: July 31, 2018 Accepted: October 03, 2018 Published: October 04, 2018 Citation: Barbach Y, Baybay H, Chaouche M, Dah Cherif A, Elloudi S, Mernissi FZ. Isolated Genital Psoriasis - Rare and Disabling Location. Int J Clin Dermatol Res. 2018;6(7):185-187. doi: http://dx.doi.org/10.19070/2332-2977-1800043 Copyright: Barbach Y © 2018. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. Introduction Psoriasis is a common chronic infammatory skin disease affect- ing 0.5-4.6% of the world population [1]. The most common form of psoriasis is chronic plaque psoriasis (PP), characterized by well-demarcated plaques with a loosely adherent silvery-white scale. The lesions are typically distributed symmetrically on the scalp, elbows, knees, lumbosacral area, and in the body folds [2]. However, psoriasis may involve all sites of the body, most fre- quently, the genitals. There are limited epidemiological data on genital involvement in psoriasis. In most cases genital involve- ment is only a part of generalized PP, often of inverse psoriasis, although it may affect only the genitals in 2-5% of the patients. Recently Meeuwis et al., [3, 4] disclosed that frequency of genital involvement was 29-40%; however, in a subsequent study they illustrated that almost 46% of 1,943 patients reported genital le- sions (GLs) at some time during the course of their skin disease. We report a case of exclusively genital psoriasis in a patient con- sulting mainly for an impairment of quality of life. Observation A 38-year-old man with no notable pathological history consulted for erythematous lesions in his newly-acquired glans (15 days) with a burning sensation, altering his life as a couple. The derma- tological examination showed the presence of 2 fnely squamous erythematous patches sitting respectively at the level of the glans and astride between the glans and the groove balano-preputial which are well limited with irregular edges making respectively 2.2 and 1.4 cm slightly infltrated, not responding to the application of healing cream [Figure 1, 2]. The rest of the mucocutaneous examination was without particularity. In this symptomatology, Paget's disease, Bowen's disease, lichen planus and genital psoria- sis had been mentioned. The latter has been confrmed by patho- logical examination [Figure 3, 4, 5]. The patient was treated with topical corticosteroids, with good clinical progress. Discussion The particular structure of the genital skin, which changes from stratifed and keratinised squamous cell epithelium to mucosa, Abstract Psoriasis is a chronic skin disease with a high impact on self-esteem and patients’ health-related quality of life. It is well known that the genital skin may be affected by psoriasis. However, little is known about the prevalence and clinical appearance of genital psoriasis, and genital skin is often neglected in the treatment of psoriatic patients. The evaluation of the impact on the quality of life of genital psoriasis is hampered by the diffculty of specifcally assessing the severity of the disease. We report a case of exclusively genital psoriasis in a patient consulting mainly for an impairment of quality of life. Keywords: Genital Psoriasis; Isolated; Quality of Life; Rare; Erectile Dysfunction. Abbreviations: PP: Plaque Psoriasis; GLs: Genital Lesions; PLs: Psoriatic Lesions; STDs: Sexually Transmitted Diseases; QoL: Quality of Life; PASI: Psoriasis Area Severity Index; BSA: Body Surface Area; PGA: Global Assessment Physician; PDI: Psoriasis Disability Index; IIEF: International Index of Erectile Function; SQOL-M: Sexual Quality of Life-Men.