SHORT REPORT Open Access Bifactor model of the CASP-12s general factor for measuring quality of life in older patients Matthew J. Kerry To the editor Patientssubscores on quality of life (QoL) measures can provide diagnostic information about strengths and weak- nesses of respondentsperformance in specific areas. Such diagnostics may help with identification of potential at-risk individuals. Subscores may also help with modify- ing extant care-treatment programs, particularly those among patient-preferred specific functionalities [1]. The Control, Autonomy, Self-realization and Pleasure (CASP) measure is one, popular QoL measure example with such subscore potential, which will be of focal interest in the current short report [2]. The CASP builds on psychology needs-satisfaction models to emphasize wellbeing across its four titled do- mains [3]. The shortened version of the original CASP-19 scale, was designed specifically for use in the Survey of Health, Ageing and Retirement in Europe (SHARE) study (CASP-12) [4], representing two combined factors: 1)Con- trol/Autonomy, and 2) Self-realization/Pleasure. Extant psychometric studies of the CASP-12 have been limited by classical measurement approaches. For example, the proposed combination of CASPs first two subscales for greater stability contradicts the retention of its other, two shorter subscales exhibiting higher internal reliabilities. Also, proposed combining (or, parceling) of items for fit- ting unidimensional prediction models potentiates further upward-bias from subdomain-criterion relations. The current short reports primary aim is to psycho- metrically inspect the CASP-12 with modern measure- ments item response theory (IRT). This is important, because increasing usage is potentially unproductive due to incomplete inspection of the CASPs internal psycho- metric structure, such as general factor strength and substantive multidimensionality [5]. This limits, among other things, the CASP-12s equating across studies that use different subsets of items, as well as hindering the CASPs expansion to new items when CASP-12s core-pool has not been IRT-calibrated. The current study will identify and extending initial findings from SHAREs older-adult general population and examine CASP-12s uni- /multi -dimensionality in a patient-spe- cific sample from the Irish Longitudinal Study on Ageing (TILDA) [6]. Since the early, 1990s days of QoL research, investiga- tors have generally agreed that physical, mental, and so- cial health subdomains are inseparable, that is, QoL is a fairly broad construct [7]. As mentioned in this authors earlier IRT evaluation of another health measure broader constructs are stabilized with broad factors [8]. As the CASPs author reassures researchers that those who simply require a single indexmay sum the CASP-12, it is important to first-determine if unidimen- sional usage in prediction models is reasonably unbiased by ignoring subdomains. As the CASP constructors con- cluded, “…strength of the inter-domain correlations. confirm our belief that QoL is a unitary phenomenon which is the product of the interactions between the do- mains[2]. This interpretation of general QoL as-caused by inter-domain interactions is important, because it contradicts the commonly accepted second-order CASP model, which hierarchically represents general QoL as causally preceding variation on its four specific domains (control, autonomy, self-realization, pleasure). If, instead, the CASPs general QoL factor is correctly interpreted as emergingfrom diverse manifestations represented by subdomains, then within-domain variation may be more accurately viewed more-so as nuisance variation that can and should be statistically treated as such in the meas- urement of QoL [9, 10]. For example, Sexton and others have suggested to covary residuals for CASPs negatively worded items arising from method effects[11]. Fitting this alternative view, the bifactor model is a viable competitor to the second-order hierarchical model that will be empirically compared on model-data fit, as well Correspondence: kerr@zhaw.ch Zurich University of Applied Sciences (ZHAW) - Institute of Health Sciences, Technikumstrasse 71, 8041 Zurich, Switzerland Journal of Patient- Reported Outcomes © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Kerry Journal of Patient-Reported Outcomes (2018) 2:57 https://doi.org/10.1186/s41687-018-0078-x