129 Winter 2018, Volume 6, Number 4 Research Paper: Comparing Two Local Aneshetic s in Third Molar Surgery With Regard to Hemodynamic Changes Ali Khalighi Sigaroodi 1,2 , Hurieh Hosseini 3,4 ,Nazanin Bashardous 1,2* 1. Assisant Professor, Dental Research Center, Guilan University of Medical Sciences, Rasht, Iran. 2. Department of Oral & Maxillofacial Medicine, School of Dentisry, Guilan University of Medical Sciences, Rasht, Iran. 3. PhD Student of Resorative Dentisry, Dental Research Center, Guilan University of Medical Sciences, Rasht, Iran. 4. PhD Student of Resorative Dentisry, Department of Oral Resorative Dentisry, School of Dentisry, Guilan University of Medical Sciences, Rasht, Iran. * Corresponding Author: Nazanin Bashardous, MD Address: Department of Oral & Maxillofacial Medicine, School of Dentisry, Guilan University of Medical Sciences, Rasht, Iran. Tel: +98 (13) 33486416 E-mail: bashardous.dental@gmail.com Introduction: Monitoring the patient’s satus is necessary during the surgical extraction of teeth, especially when the procedure is traumatic or the patient has psychological problems. Stress induced by pain during dental treatments can result in the secretion of endogenous catecholamines which in turn increases hemodynamic changes. The present sudy aimed to compare hemodynamic changes after using lidocaine-epinephrine and prilocaine-felypressin during the third lower molar surgical extraction. Materials and Methods: In this prospective randomized clinical trial, 68 patients were selected and allocated into two groups. In group I, two cartridges containing 2% lidocaine, 1.8 mL and adrenaline 1.80000 were used. In group II, the subjects received two cartridges containing 3% prilocaine with 0.03 IU/ mL of felypressin. An aneshetic technique was used for the surgical extraction of teeth. For each subject, sysolic and diasolic blood pressures, heart rate, and respiratory rate were measured three times. The mean of these three measurements were compared with that measured at the frs visit of the patient. The obtained data were analyzed using SPSS v.21. The Student t tes was applied for comparisons. Results: Statisically signifcant diferences were observed before and after using lidocaine- epinephrine in both sexes (P<0.0001) regarding the sysolic blood pressure, diasolic blood pressure and pulse rate. Conclusion: The fndings of the present sudy showed that the hemodynamic efects were not signifcantly diferent in patients receiving lidocaine with epinephrine and those receiving prilocaine with felypressin. A B S T R A C T Article info: Received: 20 Aug 2017 Accepted: 15 Nov 2017 Available Online: 01 Jan 2018 Keywords: Hemodynamic, Lidocaine, Prilocaine, Third molar Citation: ??? : Use your device to scan and read the artcle online Funding: See Page 133 Copyright: The Author(s)