Available online on www.ijcrp.com 40 THE FUNDAMENTAL & DEVELOPMENT ROLE OF EPIDURAL STEROID INJECTION IN MANAGEMENT OF HERNIATED INTERVERTEBRAL DISC WITH RADICULOPATHY Mohd.Gayoor khan 1 *, Dr. Umama Yezdani 1 , Rohit verma 2 , Mr. Ajay Kumar 2 Krishna Kumar Pandey 2 1 MRM college of pharmacy Hyderabad, Telangana 2 Truba institute of pharmacy Bhopal Madhya Pradesh Published on: 28/12/2017 Abstract Epidural steroid injection is an important modality in the conservative management of herniated intervertebral disc with radiculopathy. Epidural steroid injections (ESI) have been used since the 1950s for treatment of back pain[1,2], and it was considered from that time till now as a low-risk alternative to surgical intervention in the treatment of intervertebral disc herniation in some patients for whom non-invasive treatment has failed. It has been advocated because it modulates the body‘s response to inflammatory stimuli such as those related to a disc herniation. However, controversy still persists regarding their effectiveness in reducing the pain and improving the function with literature both supporting and opposing them are available. Keywords: epidural steroid injection, herniated intervertebral disc, radiculopathy.