Int.J.Curr.Microbiol.App.Sci (2017) 6(5): xx-xx 1 Review Article http://dx.doi.org/10.20546/ijcmas Defense Induced by Jasmonic Acid: A Review M.K. Samota 1 *, L. Bhatt 2 , N. Garg 1 and N. Geat 1 1 Division of Biochemistry, IARI, New Delhi-110012, India 2 G.B. Pant University of Agriculture and Technology - 263145, Pantnagar, India *Corresponding author: mahesh.iari1@gmail.com ABSTRACT Introduction Plants are very delicate have no opportunity other than to adapt their growth and changing with environment and need to coordinate their growth and physiology responses. Plants present in an environment in ancient time characterized by the presence of various types of stresses both biotic and abiotic. Phytohormones play important role in plant growth, development and response to stresses. Plant hormones regulate diverse developmental processes and send the signals networks in plants under different abiotic stresses. With the advancement in plant biology research it has been established that phytohormones have the potential to remove the deleterious effects posed by abiotic stresses (Masood et al., 2012; Khan et al., 2013). Plant defense responses are mediated by three major pathways of the phytohormones, jasmonic acid (JA), salicylic acid (SA) and ethylene (ET). The fine tuning of plant response to pathogen depends on the synergistic or antagonistic interactions between these three pathways (Takahashi et al., 2004). According to (Creelman and Mulpuri, 2002; Wasternack and Hause, 2002; International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 5 (2017) pp. xx-xx Journal homepage: http://www.ijcmas.com A number of novel JA derivatives have been synthesized, isolated, and characterized. A clearer picture of jasmonate biosynthesis and functions has emerged that in many respects resembles the synthesis and functions of prostaglandins and leukotrienes in mammalians. Jasmonates are produced from a-linolenic acid from lipids of damaged plant membranes. The biosynthesis of these signalling compounds can be triggered through the activation of cell membrane receptors by pathogens, peptide signals, or wounding. These jasmonates are widely distributed in plants and affect a various processes, including fruit ripening, production of viable pollen, root growth, and plant responses to wounding, abiotic stress, infections, and insects. Many of these new compounds have potent biological activity, promising that novel types of pharmacological agents possessing new mechanisms of action could soon become available. All these effects of JA are indirect, due to the well- studied induction of the biosynthesis of secondary compounds like anthocyanins, glucosinolates, terpenoids, or phenolics via transcription factors such as the Myb, Myc, and ORCA families. JA and its derivatives is widely use in daliy life as medicinal, cosmetic, and flavoring uses and other applications in agriculture systems. During the last 20 years, the many of research and inventions have showed that JA, (þ)-7-iso-JA and MJ have anticancer activity against various cancers (e.g., prostate, lymphoid, breast, blood, skin cancers, etc.). Keywords Jasmonic Acid, a-linolenic acid, leukotrienes, pharmacological agents Accepted: xx April 2017 Available Online: xx May 2017 Article Info