IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 18, Issue 1 Ser. 13 (January. 2019), PP 64-69 www.iosrjournals.org DOI: 10.9790/0853-1801136469 ww.iosrjournals.org 64 | Page Standard Formulae in Predicting Norms of Sudanese Liver Volume: A CT based study Amel Ahmed Ali Mohammed 1 , Caroline Edward Ayad 2 1 (King Khalid University, College Of Applied Medical Science –Radiology Department .Saudi-Arabia) 2 (Sudan Univesity Of Science And Technology-College Of Medical Radiological Science-Khartoum Sudan ) Corresponding Author: Amel Ahmed Ali Mohammed Abstract: This Cross-sectional, hospital-based study was obtained to establish normative data for the Computerized Tomography (CT) measurement of liver volume and dimensions in healthy Sudanese Subjects. The study took place at Alkuwaitti Specialized Hospital. The participants were 197 healthy Sudanese adults; their ages were between 18year to 82 years old. CT evaluation for the liver volume and dimensions was obtained. The liver volume was correlated with the age, gender, weight, BSA, total body water contents, Hounsfield (HU) and other liver dimensions of the participants .The current study found that the minimum liver volume was 1010 cm 3 , maximum volume was 2153cm3 and mean value of 1444.48±218.11cm3 for Sudanese populations with mean age of 44.73±16.75.This was considered greater than what was mentioned in other populations .The liver volume was significantly correlated with age at p=0.039 Right Lobe craniocaudal(CC )at p=0.000, Right Lobe antroposterior (AP)p=0.000, Right Lobe lateral (LAT)p=0.045), Left Lobe length p= 0.002 ,with no difference between the two genders except for the total body water contents at p=0.002. Two new formulae available to calculate standard liver volume for Sudanese were established. The formula are based on body surface area ,total body water , patients weight, age and liver CT number measured in HU as well as Right Lobe (CC), Right Lobe (AP),Right Lobe (LAT) and Left Lobe length. Liver Volume measured from Eastern and Western population most farley estimates liver volumes for Sudanese population, with a slight underestimation. Our formulae are acknowledged for calculating liver volume using CT scans Keywords – Liver volume, age, CT scan ,BSA --------------------------------------------------------------------------------------------------------------------------------------- Date of Submission: 11-01-2019 Date of acceptance: 27-01-2019 --------------------------------------------------------------------------------------------------------------------------------------- I. Introduction Estimation of liver measurements can be used as an index to monitor various aspects of liver disease and response to treatment. Liver size vary widely according to age. Many diseases can also affect their measurements, ranging from infection to malignant disorders [1, 2]. Palpation and percussion are the standard bedside techniques to document liver size, but are far from accurate to detect small increase in measurements [3,4] .Living donor and split-liver transplantation techniques necessitate the calculation of a standard liver volume (LV) as a reference point for the minimal volume required for the receiver. It is necessary to have a calculable LV. [5] Urata et al[6] calculated the LV from body surface area (BSA) in the Japanese population. They established a formula by means of a regression analysis of liver volume (LV) measurements using the computed tomography (CT) scans of both children and adult patients without liver abnormalities. The Japanese formula has been widely used by American, as well as European, groups working in liver transplantation. Also a formula developed by Urata et al [6]was also been used regarding that issue ,Gaucasian population have their equation with new formula for the calculation of LV was established[7] . Many formulae derived from international centers were also been used :Hashimoto et al. [8]Japan ,Vauthey et al.[9] for US ,Fu-Gui et al. [10]for Chinese, Chandramohan et al. [11]for Indian, Chan et al.[12] for Hong Kong ,A. Poovathumkadavil et al.[13]for Saudi Arabia ,and Lui SA et al[14] for South East Asian population. Imaging-based volumetry has been increasingly utilized in current clinical practice to obtain accurate measurements of the liver volume. This is particularly useful prior to major hepatic resection and living donor liver transplantation where the size of the remnant liver and liver graft, respectively, affects procedural success and postoperative death .All of the above previous studies showed that such formulae have different accuracy based on the population studied. To date, and to the best of our knowledge no such study has been carried out in Sudanese population.