Mini Review Volume 5 Issue 5 - July 2017 DOI: 10.19080/CTOIJ.2017.05.555672 Canc Therapy & Oncol Int J Copyright © All rights are reserved by Snijesh VP Breast Cancer Detection: Current Methods and Roadmap to Personalized Medicine *Snijesh VP and Manoj R Kumar Innov4Sight Health and Biomedical Systems Private Limited, India Submission: June 30, 2017; Published: July 03, 2017 * Correspondence Address: Snijesh VP, Innov4Sight Health and Biomedical Systems Private Limited, Jayanagar, Bengaluru, Karnataka, India-560041, Email: Canc Therapy & Oncol Int J 5(5): CTOIJ.MS.ID.555672 (2017) 001 Cancer Therapy & Oncology International Journal ISSN: 2473-554X Abstract Breast cancer is characterized by uncontrolled growth of malignant cells in the mammary epithelial tissue. The etiology of breast cancer is poorly understood and in spite of substantial therapeutic advances, breast cancer treatment remains as an unsolved issue. Though few genetic markers for hereditary breast cancer have been identified, the etiology of sporadic breast cancer remains poorly understood. These demands for systematic and reliable approaches to investigate the molecular mechanisms underlying the disease and identify biomarkers for better prediction of prognosis, and response to therapies. In this mini review, we highlight conventional methods used for breast cancer diagnosis and significance of personalized medicine in the cancer treatment. Keywords: Breast Cancer; Hormone Receptor Test; Cancer Genome; Personalized Medicine Abbreviations: HRT: Hormone Receptor Test; IHC: Immuno Histo Chemistry; FISH: Fluorescence In Situ Hybridization; HER2: Human Epidermal Growth Factor Receptor 2; ER: Estrogen Receptor; PR: Progesterone Receptor; NGS: Next Generation Sequencing Mini Review Figure 1: The possible factors and pathophysiology of breast cancer.