Novel Compounds in Lyophilized Female Camel Urine Khogali ME Salwa 1 , Elhassan MA bdalla 2 , Sara A Mohamed 1 and Abdallh EA Barajob 2 1 Central Veterinary Research lab, Alamarat Khartoum, Sudan 2 The National Ribat University, Faculty of Pharmacy, Khartoum, Sudan * Corresponding author: Salwa MEK, Department of Biochemistry, Nutrition, Toxicology and Pharmacology, Central Veterinary Research Laboratory, Sudan, Tel: 916742300134; E-mail: salwamuhamed@hotmail.com Received date: February 25, 2016; Accepted date: October 13, 2016; Published date: October 17, 2016 Copyright: © 2016 Salwa MEK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract The present work was done to emphasize the degraded compounds of camel urine. Lyophilized camel urine was analyzed by Gas chromatography mass spectrometry (GC-MS) Agilent 6890 GC. Eleven bioactive compounds were detected, four of these compounds have a novel structure, and these compounds are: 4-Heptanone,3-methyl, Butanoic Acid,butyl ester, Acetic Acid, (2,4,6-triethybenzoyl)thio, Benzoic Acid,methyl ester, Propane,2,2’- (methylenebis(oxy)bis(2-methyl-), Butane, 1,1-dibutoxy-, Pentanoic Acid, 4-oxo-, butyl ester, Benzoic Acid, butyl ester, Benzeneacetic Acid, 2-methylpropyl ester, Butylparaben. The four compounds of novel structure are: Titanium,(08-1,3,5,7-cyclooctatetraene)(05-2,4-cyclopentadien-1-yl),Nitroxidebis(1-1 dimethyleyl), 9,12,15- octadecatriaenoic acid, Hepta siloxane. Keywords: Camel urine; Novel compounds; Gas chromatography Introduction Urine is a purifed sterile product of blood fltration, medically referred to as plasma ultra-fltrate made by kidneys [1]. It has been shown throughout the history of medical science to this day, that urine has profound medical uses [2]. Use of animal urine is endorsed in mainstream modern medicine. Pregnant mare urine is the source of conjugated equine estrogens and has been marketed for over ffy years as pharmaceutical brand premarin, “an estrogen treatment for menopausal and pre-menopausal women” especially postpartum-one of the most prescribed drugs in United States [1]. It was very recently discovered that adding distilled cow urine to medicaments increases their efectiveness while decreasing their side-efects, making anti-cancer, anti-tubercular drug twenty times more efective and anti- bacterial eight times more efective (on line document), “urine therapy” is a stable of Ayurveda remedy [2,3]. Clinical studies on camel urine were recorded [4-10]. Te results of these experiments proved that camel urine consists of many bioactive complex compounds, which can acts against bacterial, parasitic, carcinogenic agents and it has the ability to protect the liver against toxic agents [11]. Materials and Methods Urine samples collected from natural grazing animals; then it was lyophilized using Analytical method. Analytical method Gas chromatography-Mass spectrometry (GC-MS) was performed using Agilent 6890 N network GC system interface, with a 60 m Agilent fused capillary column, DB-5 ms, 0.25 mm 1-D, 0.25 mm Film- initial temp 100°C, hold for 2 min, then programmed at 2°C/min to 300ͦc, isothermal temperature was held for 10 min. Helium carrier gas, head pressure 9.30 psi, column fow 1 ml/min. injection temp 300ͦc EL source 230°C, total scan mode was cycled at 2 seconds. 1 ml of the given sample has been diluted with 10 ml of diethyl chloromethane (DCM), and 1 µ was injected using split less mode. Results Nist library was used for the identifcation of the compounds by comparison with published retention time of the chromatogram. Corrected areas % obtained by base line subtraction was used to calculate the percentage of the compounds within the injected amount. GC-MS chromatogram of the dichloromethane extract of Camel urine, showed fourteen peaks indicating the presence of fourteen compounds. Retention time Name of compound Molecular formula Molecular weight Peak area % 8.13 Titanium C 13 H 13 Ti 217 1.33 8.84 4-Heptanone, 3-methyl C 8 H 16 O 128 2.3 Journal of Infectious Diseases and Therapy Salwa et al., J Infect Dis Ther 2016, 4:5 DOI: 10.4172/2332-0877.1000296 Research Article OMICS International J Infect Dis Ter, an open access journal ISSN:2332-0877 Volume 4 • Issue 5 • 1000296